Scientists Find First Evidence on Dental Surgeries in Ancient Egypt

Archaeologists remove the cover of an intact sarcophagus inside a tomb in Luxor, Egypt. Reuters file photo
Archaeologists remove the cover of an intact sarcophagus inside a tomb in Luxor, Egypt. Reuters file photo
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Scientists Find First Evidence on Dental Surgeries in Ancient Egypt

Archaeologists remove the cover of an intact sarcophagus inside a tomb in Luxor, Egypt. Reuters file photo
Archaeologists remove the cover of an intact sarcophagus inside a tomb in Luxor, Egypt. Reuters file photo

A virtual autopsy of the Osirmose's mummy, the doorkeeper of the Temple of Re, revealed several medical interventions in the mouth area that likely took place throughout the life of Osirmose.

This is the first evidence on the use of oral surgeries in Ancient Egypt. The studied mummy belongs to the Royal Museum of Art and History in Belgium.

Osirmose lived during the 25th dynasty, and was a member of a prominent family of Thebes' priests. His mummy was among the memorabilia of the Swedish Antiquarian Giovanni Anastasi, and was sold after his death at an auction to a Belgian antiquities collector, and then to the Royal Museum of Art and History in Belgium.

During the study, published in the latest issue of the journal Ojs earlier this month, researchers at the Saint Luc University performed a virtual autopsy on the Egyptian mummy using a three-dimensional (3D) high-resolution computed tomography (CT) scan. The taken images were later examined by a multidisciplinary team composed of radiologists, archaeologists, and oral and maxillofacial surgeons.

The researchers confirmed the mummy belonged to a man. They found the heart, aorta, and kidneys inside the mummy's body. Brain excerebration was performed, and artificial eyes were added above the stuffing of eye globes.

The teeth decay was more obvious in the upper maxilla, where the researchers discovered several anomalies including a rectangular hole on the palatine side of tooth n°26. The palatine root of tooth n°26 was missing.

Based on these findings, the researchers believe that this study provides the first evidence of a tooth removal site, and of oral surgery procedures previously conducted in old Egyptian embalmed mummy.



Blood Tests Allow 30-year Estimates of Women's Cardio Risks, New Study Says

A woman jogs in a park in Saint-Sebastien-sur-Loire near Nantes, France January 19, 2024. REUTERS/Stephane Mahe/File Photo Purchase Licensing Rights
A woman jogs in a park in Saint-Sebastien-sur-Loire near Nantes, France January 19, 2024. REUTERS/Stephane Mahe/File Photo Purchase Licensing Rights
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Blood Tests Allow 30-year Estimates of Women's Cardio Risks, New Study Says

A woman jogs in a park in Saint-Sebastien-sur-Loire near Nantes, France January 19, 2024. REUTERS/Stephane Mahe/File Photo Purchase Licensing Rights
A woman jogs in a park in Saint-Sebastien-sur-Loire near Nantes, France January 19, 2024. REUTERS/Stephane Mahe/File Photo Purchase Licensing Rights

Women’s heart disease risks and their need to start taking preventive medications should be evaluated when they are in their 30s rather than well after menopause as is now the practice, said researchers who published a study on Saturday.

Presenting the findings at the European Society of Cardiology annual meeting in London, they said the study showed for the first time that simple blood tests make it possible to estimate a woman’s risk of cardiovascular disease over the next three decades.

"This is good for patients first and foremost, but it is also important information for (manufacturers of) cholesterol lowering drugs, anti-inflammatory drugs, and lipoprotein(a)lowering drugs - the implications for therapy are broad," said study leader Dr. Paul Ridker of Brigham and Women’s Hospital in Boston, Reuters reported.

Current guidelines “suggest to physicians that women should generally not be considered for preventive therapies until their 60s and 70s. These new data... clearly demonstrate that our guidelines need to change,” Ridker said. “We must move beyond discussions of 5 or 10 year risk."

The 27,939 participants in the long-term Women’s Health Initiative study had blood tests between 1992 and 1995 for low density lipoprotein cholesterol (LDL-C or “bad cholesterol”), which are already a part of routine care.

They also had tests for high-sensitivity C-reactive protein (hsCRP) - a marker of blood vessel inflammation - and lipoprotein(a), a genetically determined type of fat.

Compared to risks in women with the lowest levels of each marker, risks for major cardiovascular events like heart attacks or strokes over the next 30 years were 36% higher in women with the highest levels of LDL-C, 70% higher in women with the highest levels of hsCRP, and 33% higher in those with the highest levels of lipoprotein(a).

Women in whom all three markers were in the highest range were 2.6 times more likely to have a major cardiovascular event and 3.7 times more likely to have a stroke over the next three decades, according to a report of the study in The New England Journal of Medicine published to coincide with the presentation at the meeting.

“The three biomarkers are fully independent of each other and tell us about different biologic issues each individual woman faces,” Ridker said.

“The therapies we might use in response to an elevation in each biomarker are markedly different, and physicians can now specifically target the individual person’s biologic problem.”

While drugs that lower LDL-C and hsCRP are widely available - including statins and certain pills for high blood pressure and heart failure - drugs that reduce lipoprotein(a) levels are still in development by companies, including Novartis , Amgen , Eli Lilly and London-based Silence Therapeutics.

In some cases, lifestyle changes such as exercising and quitting smoking can be helpful.

Most of the women in the study were white Americans, but the findings would likely “have even greater impact among Black and Hispanic women for whom there is even a higher prevalence of undetected and untreated inflammation,” Ridker said.

“This is a global problem,” he added. “We need universal screening for hsCRP ... and for lipoprotein(a), just as we already have universal screening for cholesterol.”