Moderna Signs Deal on Variant-Adapted COVID Shots for World’s Poorest

A bottle containing the new Moderna Spikevax mRNA COVID 19 vaccine stands ready to be drawn into syringes at the centre of the Geneva University Hospitals (HUG), that opened for the public to get the forth booster dose againt COVID, in Geneva, Switzerland, 10 October 2022. (EPA)
A bottle containing the new Moderna Spikevax mRNA COVID 19 vaccine stands ready to be drawn into syringes at the centre of the Geneva University Hospitals (HUG), that opened for the public to get the forth booster dose againt COVID, in Geneva, Switzerland, 10 October 2022. (EPA)
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Moderna Signs Deal on Variant-Adapted COVID Shots for World’s Poorest

A bottle containing the new Moderna Spikevax mRNA COVID 19 vaccine stands ready to be drawn into syringes at the centre of the Geneva University Hospitals (HUG), that opened for the public to get the forth booster dose againt COVID, in Geneva, Switzerland, 10 October 2022. (EPA)
A bottle containing the new Moderna Spikevax mRNA COVID 19 vaccine stands ready to be drawn into syringes at the centre of the Geneva University Hospitals (HUG), that opened for the public to get the forth booster dose againt COVID, in Geneva, Switzerland, 10 October 2022. (EPA)

Moderna Inc has agreed to provide its new variant-adapted COVID-19 vaccine to the global scheme aiming to deliver shots to the world's poorest people.

The biotech company and vaccine alliance GAVI will cancel their existing supply deal for vaccines based on the original coronavirus strain. Instead, Moderna will supply up to 100 million doses of its new, variant-adapted vaccines at its lowest available price from 2023.

GAVI leads the COVAX initiative alongside the World Health Organization and other global bodies. The scheme has delivered 1.79 billion doses of COVID vaccine to 146 countries, including nearly 186 million doses of Moderna's original shot.

While at first the initiative struggled for shots as wealthy countries snapped up limited supply, this year it has had a glut of the original vaccines, prompting negotiations to try to better align supply with demand.

Moderna's bivalent COVID vaccine, containing both the original coronavirus strain and the BA.1 Omicron variant, has had approval from regulators worldwide.

GAVI chief executive Seth Berkley said the new agreement was a "critical step for equitable access" to allow lower income countries to use the modified vaccines as they see fit.

Many wealthier countries have started using the vaccine in booster campaigns.

Negotiations with other vaccine manufacturers to adjust supply agreements are going on, GAVI said.



Bavarian Nordic to Ramp up Production of Mpox Vaccine

An employee of the vaccine company Bavarian Nordic works in a laboratory of the company in Martinsried near Munich, Germany, May 24, 2022. REUTERS/Lukas Barth/File Photo Purchase Licensing Rights
An employee of the vaccine company Bavarian Nordic works in a laboratory of the company in Martinsried near Munich, Germany, May 24, 2022. REUTERS/Lukas Barth/File Photo Purchase Licensing Rights
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Bavarian Nordic to Ramp up Production of Mpox Vaccine

An employee of the vaccine company Bavarian Nordic works in a laboratory of the company in Martinsried near Munich, Germany, May 24, 2022. REUTERS/Lukas Barth/File Photo Purchase Licensing Rights
An employee of the vaccine company Bavarian Nordic works in a laboratory of the company in Martinsried near Munich, Germany, May 24, 2022. REUTERS/Lukas Barth/File Photo Purchase Licensing Rights

Danish biotech firm Bavarian Nordic said on Saturday it plans to ramp up production of its mpox vaccine and work with international health organizations to ensure fair access as the disease has been declared a global public health emergency.

The company, one of the few drug firms that have an mpox vaccine, said it has informed the Africa Centers for Disease Control and Prevention (CDC) that it can manufacture 10 million doses of the vaccine by the end of 2025, and could already supply up to 2 million doses this year.

The company said that it is expanding its production network to include Africa, and is prepared to work with Africa CDC as well as the World Health Organization (WHO) to make the vaccine accessible to all countries, Reuters reported.

Earlier this week, the WHO declared mpox a global public health emergency for the second time in two years.

The viral infection, which causes pus-filled lesions and flu-like symptoms, is usually mild but can kill. Two strains are now spreading in Congo and neighboring countries - the endemic form of the virus, clade I, and a new offshoot called clade Ib.

There have been 27,000 cases and more than 1,100 deaths, mainly among children, in Congo since the current outbreak began in January 2023.