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Moderna Signs Deal on Variant-Adapted COVID Shots for World’s Poorest

A bottle containing the new Moderna Spikevax mRNA COVID 19 vaccine stands ready to be drawn into syringes at the centre of the Geneva University Hospitals (HUG), that opened for the public to get the forth booster dose againt COVID, in Geneva, Switzerland, 10 October 2022. (EPA)
A bottle containing the new Moderna Spikevax mRNA COVID 19 vaccine stands ready to be drawn into syringes at the centre of the Geneva University Hospitals (HUG), that opened for the public to get the forth booster dose againt COVID, in Geneva, Switzerland, 10 October 2022. (EPA)
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Moderna Signs Deal on Variant-Adapted COVID Shots for World’s Poorest

A bottle containing the new Moderna Spikevax mRNA COVID 19 vaccine stands ready to be drawn into syringes at the centre of the Geneva University Hospitals (HUG), that opened for the public to get the forth booster dose againt COVID, in Geneva, Switzerland, 10 October 2022. (EPA)
A bottle containing the new Moderna Spikevax mRNA COVID 19 vaccine stands ready to be drawn into syringes at the centre of the Geneva University Hospitals (HUG), that opened for the public to get the forth booster dose againt COVID, in Geneva, Switzerland, 10 October 2022. (EPA)

Moderna Inc has agreed to provide its new variant-adapted COVID-19 vaccine to the global scheme aiming to deliver shots to the world's poorest people.

The biotech company and vaccine alliance GAVI will cancel their existing supply deal for vaccines based on the original coronavirus strain. Instead, Moderna will supply up to 100 million doses of its new, variant-adapted vaccines at its lowest available price from 2023.

GAVI leads the COVAX initiative alongside the World Health Organization and other global bodies. The scheme has delivered 1.79 billion doses of COVID vaccine to 146 countries, including nearly 186 million doses of Moderna's original shot.

While at first the initiative struggled for shots as wealthy countries snapped up limited supply, this year it has had a glut of the original vaccines, prompting negotiations to try to better align supply with demand.

Moderna's bivalent COVID vaccine, containing both the original coronavirus strain and the BA.1 Omicron variant, has had approval from regulators worldwide.

GAVI chief executive Seth Berkley said the new agreement was a "critical step for equitable access" to allow lower income countries to use the modified vaccines as they see fit.

Many wealthier countries have started using the vaccine in booster campaigns.

Negotiations with other vaccine manufacturers to adjust supply agreements are going on, GAVI said.

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Varieties

Storm Dumps Record Rain in Northern California, While US Northeast Deals with Winter Storms

A pedestrian walks along a flooded street during a storm Thursday, Nov. 21, 2024, in Santa Rosa, Calif. (AP Photo/Jeff Chiu)
A pedestrian walks along a flooded street during a storm Thursday, Nov. 21, 2024, in Santa Rosa, Calif. (AP Photo/Jeff Chiu)
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Storm Dumps Record Rain in Northern California, While US Northeast Deals with Winter Storms

A pedestrian walks along a flooded street during a storm Thursday, Nov. 21, 2024, in Santa Rosa, Calif. (AP Photo/Jeff Chiu)
A pedestrian walks along a flooded street during a storm Thursday, Nov. 21, 2024, in Santa Rosa, Calif. (AP Photo/Jeff Chiu)

A major storm dropped more snow and record rain in California, causing small landslides and flooding some streets, while on the opposite side of the country blizzard or winter storm warnings were in effect Saturday for areas spanning from the Northeast to central Appalachia.
The storm on the West Coast arrived in the Pacific Northwest earlier this week, killing two people and knocking out power to hundreds of thousands, mostly in the Seattle area, before its strong winds moved through Northern California, The Associated Press reported.
Santa Rosa, California, saw its wettest three-day period on record with about 12.5 inches (32 centimeters) of rain falling by Friday evening, according to the National Weather Service in the Bay Area.
Flooding closed part of scenic Highway 1, also known as the Pacific Coast Highway, in Mendocino County and there was no estimate for when it would reopen, according to the California Department of Transportation.
On the East Coast, another storm brought much-needed rain to New York and New Jersey, where rare wildfires have raged in recent weeks, and heavy snow to northeastern Pennsylvania. Parts of West Virginia were under a blizzard warning through Saturday morning, with up to 2 feet (61 centimeters) of snow and high winds making travel treacherous.
As residents in the Seattle area headed into the weekend, more than 112,000 people were still without power from this season’s strongest atmospheric river — a long plume of moisture that forms over an ocean and flows through the sky over land. Crews worked to clear streets of downed lines, branches and other debris, while cities opened warming centers so people heading into their fourth day without power could get warm food and plug in their cellphones and other devices.
Gale warnings were issued off Washington, Oregon and California, and high wind warnings were in effect across parts of Northern California and Oregon. There were winter storm warnings for parts of the California Cascades and the Sierra Nevada.
Forecasters predicted that both coasts would begin to see a reprieve from the storms as the system in the northeast moves into eastern Canada and the one in the West heads south.
By Friday night, some relief was already being seen in California, where the sheriff’s office in Humboldt County downgraded evacuation orders to warnings for people near the Eel River after forecasters said the waterway would see moderate but not major flooding.
The system roared ashore on the West Coast on Tuesday as a “ bomb cyclone,” which occurs when a cyclone intensifies rapidly. It unleashed fierce winds that toppled trees onto roads, vehicles and homes.
Debra Campbell said she was sitting in the dark with a flashlight that night, unable to sleep as strong winds lashed her house in Crescent City, California. With a massive boom, a 150-foot (46-meter) tree came crashing down on her home and car.
“It was just so incredibly frightening,” AP quoted Campbell as saying. “Once I realized it wasn’t going to come through the ceiling where I was at, I was able to grab my car keys and my purse. ... And I open the front door and it’s just solid tree.”
In the Northeast, which has been hit by drought, more than 2 inches (5 centimeters) of rain was expected by Saturday morning north of New York City, with snow mixed in at higher elevations.
Despite the mess, the precipitation was expected to help ease drought conditions in a state that has seen an exceptionally dry fall.
“It’s not going to be a drought buster, but it’s definitely going to help when all this melts,” said Bryan Greenblatt, a National Weather Service meteorologist in Binghamton, New York.
Heavy snow fell in northeastern Pennsylvania, including the Pocono Mountains, prompting a raft of school closures. Higher elevations reported up to 17 inches (43 centimeters), with lesser accumulations in valley cities like Scranton and Wilkes-Barre. More than 85,000 customers in 10 counties lost power, and the state transportation department imposed speed restrictions on some highways.