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Hevolution CEO Discusses Career in Innovation, Medicine, and Business

Dr. Mehmood Khan, CEO of the Hevolution Foundation
Dr. Mehmood Khan, CEO of the Hevolution Foundation
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Hevolution CEO Discusses Career in Innovation, Medicine, and Business

Dr. Mehmood Khan, CEO of the Hevolution Foundation
Dr. Mehmood Khan, CEO of the Hevolution Foundation

Dr. Mehmood Khan, CEO of the Hevolution Foundation, the largest philanthropy organization funding aging medicine in the world, expressed that receiving Saudi citizenship will boost his scientific and practical capabilities.
He said this new status will help him advance his research, especially in addressing aging.
This comes as part of a recent royal decree granting Saudi citizenship to several notable scholars, doctors, researchers, and innovators.
“Our Chairman, his Royal Highness (Crown Prince Mohammed bin Salman), has very high expectations of our work and the impact we need to do; We were created in part because of his vision,” Khan told Asharq Al-Awsat.
“Living up to the expectations and challenges we get faced with is itself exciting, but it is challenging,” revealed Khan, affirming that Hevolution’s team is “up to that task.”
Khan, who has experience in both corporate and medical fields, told Asharq Al-Awsat that his work across academic, public, and private sectors has been a continuous learning process, with each area enhancing the others.
According to the CEO, these industries are interconnected, and combining their strengths often leads to the best solutions.
This insight inspired the Hevolution initiative, which brings together the scientific community, NGOs, pharmaceutical companies, policymakers, academia, biotech firms, CEOs, and others to promote healthy aging.
Khan highlighted the value of integrating insights from different sectors.
Academia provides detailed research, the public sector offers insights on population health and regulations, and the corporate world brings innovation and efficiency, explained Khan, adding that by merging these perspectives, the world can tackle complex health challenges more effectively.
“We’ve been working through, and are now investing, funding and partnering with over 200 scientists around the world, and over 150 different university labs,” said Khan.
Hevolution uses this integrated approach to advance healthy aging.
This initiative embodies my passion for addressing major challenges and offers a significant opportunity to make a global impact.
Khan talked about the first $400 million commitment Hevolution made in the last 23 months, calling it “unprecedented.”
“There has never been a non-profit organization in the world that has gone from not existing to now becoming the largest philanthropy funding aging biology and medicine in the world,” affirmed Khan.
Khan stressed that work at Hevolution not only pushes scientific boundaries but also promotes cross-sector collaboration to improve global health outcomes.
Since Khan’s early days in medical school, he’s been deeply interested in nutrition and population health, which was an unconventional focus back then. This journey set the foundation for his later work in community health.
Khan’s time as an endocrinology faculty member at the Mayo Clinic was crucial. He led programs on diabetes, endocrine diseases, metabolism, and nutrition, which strengthened his expertise in designing disease prevention systems.
In the private sector, Khan took on a key role at Takeda Pharmaceutical as the global head of R&D, which shaped his approach to innovative healthcare solutions.
At PepsiCo, as Chief Scientific Officer, he learned crucial principles of scale, impact, transformation, and tackling global challenges.
As CEO of Hevolution, Khan uses all his professional experience to advance the foundation’s mission of developing health sciences to address age-related diseases.
Khan serves on the boards of Reckitt Benckiser and the Saudi Research, Development, and Innovation Authority (RDIA).
He is the CEO of Life Biosciences, a member of Saudi Arabia’s biotechnology strategy committee, and the chair of the advanced technology visiting committee at the US National Institute of Standards and Technology (NIST).
Khan told Asharq Al-Awsat that he feels honored to have recently become a Saudi citizen by royal decree, while also holding dual US and UK citizenship. This helps him lead Hevolution effectively and work closely with international partners.
Khan commented on his recent Saudi citizenship, saying that in addition to feeling honored to receive Saudi citizenship by royal decree, alongside other distinguished individuals, this recognition is a great privilege.
Being a Saudi citizen, as per Khan, is a significant milestone and acknowledges the progress in his work in aging science and global health. It also strengthens Khan’s commitment to the work at Hevolution.
Khan noted that this new status enhances his ability to build relationships and collaborate within the Kingdom and internationally. It offers a deeper connection with the local community and better opportunities to engage with policymakers and leaders.
He also said that this recognition boosts Hevolution’s global presence and credibility, making the foundation’s collaborations with international scientists and business leaders stronger. It positions Hevolution as a key player in addressing age-related diseases.
Khan emphasized that this honor reflects the hard work and innovation of Hevolution’s entire team.
The CEO said that it was collective efforts that have made this achievement possible.
Khan also said he is excited to engage more deeply with the scientific and medical community in the Kingdom, adding that his new citizenship helps him contribute to Vision 2030 and the national biotechnology strategy, promoting innovation and attracting top global talent.

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Interviews

Fakhri Karim: I Conveyed Talabani’s Advice to Assad on Terrorists

Fakhri Karim (Asharq Al-Awsat)
Fakhri Karim (Asharq Al-Awsat)
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Fakhri Karim: I Conveyed Talabani’s Advice to Assad on Terrorists

Fakhri Karim (Asharq Al-Awsat)
Fakhri Karim (Asharq Al-Awsat)

The late Iraqi President, Jalal Talabani, excelled at delivering messages subtly. In private meetings, he spoke more freely than in public statements or interviews. His chief advisor, Fakhri Karim, often joined these discussions.

Luncheons were lavish, showing Talabani's respect for different opinions, though he rarely followed doctors’ advice.

Talabani believed that Iranian leaders were smart and hoped they wouldn’t try to control Baghdad from Tehran, citing the failed attempt to manage Beirut from Damascus.

He noted that Iraq’s independent spirit makes it hard for the country to follow the US, Iran, or Türkiye. Talabani also admitted giving refuge to 80 Iraqi officers who had fought against Iran, after they were targeted by certain groups.

Talabani praised Syria’s late President Hafez al-Assad for his invaluable support, providing accommodation and passports.

Speaking to Asharq Al-Awsat, Karim revealed he had warned President Bashar al-Assad, on behalf of Talabani, that militants allowed into Iraq to fight US forces might later turn against Syria.

This, Karim noted, did happen.

After the Israeli invasion of Beirut in 1982, Karim relocated to Damascus. There, he expanded his Al-Mada organization, focusing on publishing, translation, and organizing book fairs, alongside his political activities.

This allowed him to build relationships with top civilian and military officials.

In 2000, after Bashar al-Assad came to power, he met with Karim.

“I felt Assad was eager to listen, especially given my connections with many intellectuals,” recalled Karim.

“I told him dissenting voices exist but are mostly positive. You talk about modernization and renewal; this is a chance for some openness, even in elections,” Karim said he told Assad.

“Do you think anyone could really compete with you, given your position as the Baath Party's leader with all its resources?” Karim questioned.

Karim then discussed the situation of Syrian Kurds with Assad, noting that many lack identification papers, even basic travel documents. He also mentioned seeing historic Kurdish areas in the Khabur region with their names changed to Arabic, which causes sensitivities.

“I am not satisfied with this situation. Rest assured, this issue is on my agenda, and you will hear positive news about it,” Karim cited Assad as saying at the time.

In a later meeting, after the change in Iraq, Karim met Assad several times.

On one occasion, Karim recalls conveying Talabani’s greetings and concerns about armed fighters moving into Iraq and the dangers this posed to both Iraq and possibly Syria.

“We have deployed large forces to secure the borders, but what can we do? There are tribes and smugglers,” Assad complained about the situation.

“I told President Assad that as Fakhri Karim, I couldn’t share with the Americans what I know. I assured him that terrorists enter Iraq from a specific location I’m familiar with, not from all borders,” Karim recounted to Asharq Al-Awsat.

“I also noted that Syria tightly controls its airspace, shooting down any foreign aircraft,” he added.

Assad then responded to Karim and said: “We’re prepared, let us know what we can do.”

In reality, Damascus was worried because there were reports suggesting that Syria’s Baath regime could be the next target for the US army at its borders. Additionally, Damascus was concerned about the sectarian divisions—Shiite, Sunni, and Kurdish—in dealing with Iraq and the potential impact on Syria.

Repairing Kurdish Relations

Karim has spent years working on repairing the relationship between Kurdish leaders Talabani and Masoud Barzani.

This history began with the split that gave rise to the ‘Patriotic Union of Kurdistan’ from the ‘Kurdistan Democratic Party.’

Despite bloody conflicts and external meddling, Karim believes Kurdish leaders unify in the face of danger to their people and region, a pattern he expects to continue.

Karim believes that the Kurdish leadership, symbolized by Masoud Barzani and Jalal Talabani, made a big mistake at the beginning by focusing only on regional issues, ignoring Baghdad’s affairs.

He thinks they should have aimed for a federal democratic system that respects citizenship rights.

Karim pointed out that without a unified Iraq, the region’s rights would be uncertain. He also criticized the Shiite-Kurdish alliance, which he sees as odd.

Additionally, he mentioned mistakes in failing to unify regional institutions and increasing corruption, with party interests often trumping competence in appointments.

Asked about the personal bond between Talabani and Barzani, Karim said: “Both have moved past their tough history, but they haven’t done enough for the future.”

“I want to highlight an act by Barzani that shows his character. When Talabani was sick, Barzani made it clear to anyone thinking of harming Talabani or his family that there would be consequences,” he revealed.

“This isn’t hearsay, it’s firsthand,” affirmed Karim.

“Barzani also refused to discuss the presidency or a successor during Talabani’s illness. I personally organized a gathering for Talabani’s family, where Barzani reassured them, ‘I’m here for you, I’m family.’ His words moved everyone, showing a strong emotional connection,” he added.

When asked about Barzani’s character, Karim said: “He's been a long-time friend, and our relationship has been politically aligned and personally warm from the start.”

“I see him as a loyal friend, and he's shown that loyalty on multiple occasions. He’s smart, decisive, and listens carefully, often changing his mind after thorough consideration,” he noted.

“Once Barzani commits to something, he finds it hard to go back on his word. There was a moment during negotiations with Saddam Hussein when he stood firm despite my advice to reconsider,” recalled Karim.

Regarding the aftermath of the independence referendum, Karim believes that the negative turn in the political landscape began during Nouri al-Maliki’s tenure.

Al-Maliki’s attempts to shift alliances and his refusal to compromise exacerbated tensions.

The referendum itself wasn’t the problem; rather, it was exploited by some to punish the Kurdistan Region.

However, Karim emphasized that holding referendums is a citizen’s right, and the purpose of the Kurdistan referendum was to affirm this right, not to declare independence.