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Hevolution CEO Discusses Career in Innovation, Medicine, and Business

Dr. Mehmood Khan, CEO of the Hevolution Foundation
Dr. Mehmood Khan, CEO of the Hevolution Foundation
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Hevolution CEO Discusses Career in Innovation, Medicine, and Business

Dr. Mehmood Khan, CEO of the Hevolution Foundation
Dr. Mehmood Khan, CEO of the Hevolution Foundation

Dr. Mehmood Khan, CEO of the Hevolution Foundation, the largest philanthropy organization funding aging medicine in the world, expressed that receiving Saudi citizenship will boost his scientific and practical capabilities.
He said this new status will help him advance his research, especially in addressing aging.
This comes as part of a recent royal decree granting Saudi citizenship to several notable scholars, doctors, researchers, and innovators.
“Our Chairman, his Royal Highness (Crown Prince Mohammed bin Salman), has very high expectations of our work and the impact we need to do; We were created in part because of his vision,” Khan told Asharq Al-Awsat.
“Living up to the expectations and challenges we get faced with is itself exciting, but it is challenging,” revealed Khan, affirming that Hevolution’s team is “up to that task.”
Khan, who has experience in both corporate and medical fields, told Asharq Al-Awsat that his work across academic, public, and private sectors has been a continuous learning process, with each area enhancing the others.
According to the CEO, these industries are interconnected, and combining their strengths often leads to the best solutions.
This insight inspired the Hevolution initiative, which brings together the scientific community, NGOs, pharmaceutical companies, policymakers, academia, biotech firms, CEOs, and others to promote healthy aging.
Khan highlighted the value of integrating insights from different sectors.
Academia provides detailed research, the public sector offers insights on population health and regulations, and the corporate world brings innovation and efficiency, explained Khan, adding that by merging these perspectives, the world can tackle complex health challenges more effectively.
“We’ve been working through, and are now investing, funding and partnering with over 200 scientists around the world, and over 150 different university labs,” said Khan.
Hevolution uses this integrated approach to advance healthy aging.
This initiative embodies my passion for addressing major challenges and offers a significant opportunity to make a global impact.
Khan talked about the first $400 million commitment Hevolution made in the last 23 months, calling it “unprecedented.”
“There has never been a non-profit organization in the world that has gone from not existing to now becoming the largest philanthropy funding aging biology and medicine in the world,” affirmed Khan.
Khan stressed that work at Hevolution not only pushes scientific boundaries but also promotes cross-sector collaboration to improve global health outcomes.
Since Khan’s early days in medical school, he’s been deeply interested in nutrition and population health, which was an unconventional focus back then. This journey set the foundation for his later work in community health.
Khan’s time as an endocrinology faculty member at the Mayo Clinic was crucial. He led programs on diabetes, endocrine diseases, metabolism, and nutrition, which strengthened his expertise in designing disease prevention systems.
In the private sector, Khan took on a key role at Takeda Pharmaceutical as the global head of R&D, which shaped his approach to innovative healthcare solutions.
At PepsiCo, as Chief Scientific Officer, he learned crucial principles of scale, impact, transformation, and tackling global challenges.
As CEO of Hevolution, Khan uses all his professional experience to advance the foundation’s mission of developing health sciences to address age-related diseases.
Khan serves on the boards of Reckitt Benckiser and the Saudi Research, Development, and Innovation Authority (RDIA).
He is the CEO of Life Biosciences, a member of Saudi Arabia’s biotechnology strategy committee, and the chair of the advanced technology visiting committee at the US National Institute of Standards and Technology (NIST).
Khan told Asharq Al-Awsat that he feels honored to have recently become a Saudi citizen by royal decree, while also holding dual US and UK citizenship. This helps him lead Hevolution effectively and work closely with international partners.
Khan commented on his recent Saudi citizenship, saying that in addition to feeling honored to receive Saudi citizenship by royal decree, alongside other distinguished individuals, this recognition is a great privilege.
Being a Saudi citizen, as per Khan, is a significant milestone and acknowledges the progress in his work in aging science and global health. It also strengthens Khan’s commitment to the work at Hevolution.
Khan noted that this new status enhances his ability to build relationships and collaborate within the Kingdom and internationally. It offers a deeper connection with the local community and better opportunities to engage with policymakers and leaders.
He also said that this recognition boosts Hevolution’s global presence and credibility, making the foundation’s collaborations with international scientists and business leaders stronger. It positions Hevolution as a key player in addressing age-related diseases.
Khan emphasized that this honor reflects the hard work and innovation of Hevolution’s entire team.
The CEO said that it was collective efforts that have made this achievement possible.
Khan also said he is excited to engage more deeply with the scientific and medical community in the Kingdom, adding that his new citizenship helps him contribute to Vision 2030 and the national biotechnology strategy, promoting innovation and attracting top global talent.

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Fakhri Karim: My Complaint to Sistani on Corruption Spurred Suggestion of Saddam-Era Minister

Fakhri Karim, senior adviser to late Iraqi President Jalal Talabani, speaks to Asharq Al-Awsat. (Asharq Al-Awsat)
Fakhri Karim, senior adviser to late Iraqi President Jalal Talabani, speaks to Asharq Al-Awsat. (Asharq Al-Awsat)
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Fakhri Karim: My Complaint to Sistani on Corruption Spurred Suggestion of Saddam-Era Minister

Fakhri Karim, senior adviser to late Iraqi President Jalal Talabani, speaks to Asharq Al-Awsat. (Asharq Al-Awsat)
Fakhri Karim, senior adviser to late Iraqi President Jalal Talabani, speaks to Asharq Al-Awsat. (Asharq Al-Awsat)

In post-Saddam Hussein Iraq, the prime minister's office gained significant power. It became customary for the prime minister to be Shiite, the president Kurdish, and the speaker of Parliament Sunni.

This power-sharing arrangement, focusing on sectarian representation over institutional structure, has remained strong.

Attempts to break this norm have failed, including when former US President Barack Obama and his Vice President Joe Biden tried to support Ayad Allawi, a Shiite politician, for the presidency. The aim was to keep Prime Minister Nouri al-Maliki in power with support from both Washington and Tehran.

Despite Allawi’s parliamentary majority win, he didn’t become president.

Arab states were slow to react to changes in Iraq, allowing Iran to step in. Iran supported the US-created Iraqi Governing Council and sought to bring together Shiite factions to join the political process.

Its influence grew due to its backing of groups that opposed Saddam Hussein. Iran gained a key role in Iraq, effectively having veto power over decisions and a say in forming governments, while also expecting an eventual US military withdrawal.

Fakhri Karim, senior adviser to late Iraqi President Jalal Talabani, said Iran stepped in to fill a vacuum in Iraq, solidifying its role and protecting its interests.

This made Iran’s Quds Force commander Gen. Qassem Soleimani a key figure in Iraq, shaping everything from the reduction of US military presence to the formation of governments.

A foreign power’s influence in a neighboring country grows only if locals accept its role.

Soleimani and deputy leader of Iraq’s Popular Mobilization Forces (PMF) Abu Mahdi al-Muhandis were killed in a US strike near Baghdad airport in January 2020.

Speaking to Asharq Al-Awsat, Karim noted that Soleimani “was dedicated to serving his country’s interests, and the other side should have defended its own role and interests.”

He recalled Soleimani as being “skilled, effective, and able to earn trust, shifting from flexibility to rigidity when needed.”

This was clear in a letter Soleimani sent to Talabani when he considered supporting a no-confidence motion against Maliki’s government.

Karim also mentioned that al-Muhandis was deeply trusted by the Iranian general.

Talabani assigned his senior adviser various missions in Iran, focusing on forming Iraqi governments and relations with Kurdistan.

During a visit to Tehran, Adil Abdul Mahdi, who would later become prime minister, informed Talabani and Karim that “Soleimani’s claim that Iran supports Nouri al-Maliki for prime minister is false.”

“I was told that Iranian Supreme Leader Ali Khamenei supports me,” argued Abdul Mahdi at the time.

Talabani felt awkward despite being close to Abdul Mahdi. He asked Karim to visit Tehran, where he met Soleimani and al-Muhandis. Soleimani denied Abdul Mahdi’s claims, saying he could take Karim to the Supreme Leader to hear the truth.

For his part, Karim said the Supreme Council didn’t support al-Maliki and that influential cleric Moqtada al-Sadr’s stance was hardening. Soleimani assured that the Iranians were in contact with al-Sadr and would handle the issue of the Supreme Council.

When Karim returned, he informed Talabani and Kurdish leader Masoud Barzani that the Badr Organization, led by Hadi al-Amiri, had left the Supreme Council to join Maliki, shifting the balance and allowing the formation of a government without the Council’s interference.

Karim remembered that Iran initially supported Ibrahim al-Jaafari for prime minister (2005-2006). However, Jaafari quickly became a burden on the political process and Shiite leaders then signaled the need for change.

The US Ambassador advised Jaafari to resign, threatening him if he didn't comply.

Maliki’s name wasn’t initially considered; Ali al-Adib from the “Dawa” party, of which Maliki was a member, was the favored choice. But Maliki didn’t support Adib, so after deliberations, the party settled on Maliki instead.

Breakfast with Soleimani

Karim remembers a breakfast meeting with Soleimani and al-Muhandis. He brought up Maliki’s performance during his second term and the widespread corruption in Iraq.

Soleimani suggested discussing it further, but Karim insisted the issue was urgent.

He questioned why, if all major Shiite forces agreed, change couldn’t happen. Soleimani indicated that decisions within the Shiite alliance were made by those who remained in it, prompting Karim to ask if Soleimani was implying it was him. Soleimani then replied : “Think what you wish.”

Sadr’s misstep

In the post-Saddam Hussein era, Sadr emerged as a major political force in Iraq. He led a large popular and armed movement.

Dealing with Sadr was challenging for political factions, especially among Shiites. Some disputes even culminated in armed conflicts. Managing Sadr’s influence was difficult both internally and for external interests, especially given his unpredictability.

When asked about Sadr’s decision to quit politics in 2022, Karim called it a major mistake.

He believed Iraq suffered greatly from this move, as it left parliament without any influential Shiite force capable of standing up against decisions not aligned with common goals.

Karim highlighted that filling seats with losing candidates seemed odd and turned the minority into the majority, undermining the constitutional process. He also noted the Shiite community’s fragmentation, with many Shiites not participating in recent elections due to their disenchantment with the political parties.

Karim warned against underestimating the potential for renewed protests and uprisings among the marginalized against the government and ruling powers.

Sistani’s unexpected proposal

When discussing top Shiite Religious Authority in Iraq, Ali al-Sistani, Karim highlighted his political astuteness, surpassing the majority of other Shiite leaders. Sistani’s Friday sermons, delivered by his representatives, reflect this forward-thinking approach.

Karim noted a key observation about Sistani’s mindset. Despite corruption concerns, Sistani surprised Karim by suggesting bringing back the former Minister of Trade for his effectiveness in managing the ration card distribution.

He even proposed considering a Christian minister if they were honest and prioritized the people’s interests.

Furthermore, Sistani emphasized the importance of inclusivity in the new Iraq, advocating for the rights of Sunni and Kurdish components. He rejected marginalization and insisted on their participation and rights.

Sistani’s fatwa and the PMF

Karim believes that Sistani issued a fatwa on “jihad” to rally people against the significant threat posed by ISIS in 2014. He didn’t specifically mention the Popular Mobilization Forces (PMF) or any other organization but referred to volunteers.

“Many responded to Sistani’s call and made significant sacrifices alongside the armed forces and Peshmerga. Volunteers participated in liberating areas once occupied by the terror group,” said Karim.

Karim further noted that there was a belief that those who made sacrifices had the right to be part of the armed forces and receive state support.

“The idea of integrating militias or military entities into the armed forces is not new,” explained Karim.

“US diplomat Paul Bremer [the first post-invasion governor of Iraq] proposed something similar to factions and organizations under the banner of integration into the army, and steps were taken in this direction,” he added.

“The goal was to eliminate the threat of ISIS, not to create a parallel army or establish another institution.”