Iran's foreign ministry said no one had held any expectation that talks with the United States could have reached an agreement within one session after the negotiations in Islamabad stalled on Sunday.
"Naturally, from the beginning we should not have expected to reach an agreement in a single session. No one had such an expectation," ministry spokesperson Esmaeil Baqaei said, according to state broadcaster IRIB.
He said Tehran was "confident that contacts between us and Pakistan, as well as our other friends in the region, will continue.”
Iran's semi-official Tasnim news agency said that "excessive" US demands had hindered reaching an agreement. Other Iranian media said there was agreement on a number of issues but that the Strait of Hormuz and Iran's nuclear program were the main points of difference.
"The bad news is that we have not reached an agreement, and I think that's bad news for Iran much more than it's bad news for the United States of America," Vice President JD Vance, the head of the US delegation, told reporters shortly before he left Islamabad.
In his brief press conference, Vance did not mention reopening the Strait of Hormuz, a choke point for about 20% of global energy supplies that Tehran has blocked since the war began.
Vance said he had spoken with President Donald Trump as many as a dozen times during the talks. But even as the negotiations continued, Trump said on Saturday that a deal was not entirely necessary.