AI Helps Fuel New Era of Medical Self-testing

Neurable research scientist Alicia Howell-Munson demonstrates the company's headset, which it says can detect early signs of Alzheimer's disease. Patrick T. Fallon / AFP
Neurable research scientist Alicia Howell-Munson demonstrates the company's headset, which it says can detect early signs of Alzheimer's disease. Patrick T. Fallon / AFP
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AI Helps Fuel New Era of Medical Self-testing

Neurable research scientist Alicia Howell-Munson demonstrates the company's headset, which it says can detect early signs of Alzheimer's disease. Patrick T. Fallon / AFP
Neurable research scientist Alicia Howell-Munson demonstrates the company's headset, which it says can detect early signs of Alzheimer's disease. Patrick T. Fallon / AFP

Beyond smart watches and rings, artificial intelligence is being used to make self-testing for major diseases more readily available -- from headsets that detect early signs of Alzheimer's to an iris-scanning app that helps spot cancer.

"The reason preventive medicine doesn't work right now is because you don't want to go to the doctor all the time to get things tested," says Ramses Alcaide, co-founder and CEO of startup Neurable.

"But what about if you knew when you needed to go to the doctor?"

Connected rings, bracelets and watches -- which were everywhere at last week's Consumer Electronics Show in Las Vegas -- can already monitor heart rate, blood pressure and glucose levels, with varying degrees of accuracy.

These gadgets are in high demand from consumers. A recent study published by OpenAI showed that more than 200 million internet users check ChatGPT every week for information on health topics.

On Wednesday, OpenAI even launched a chatbot that can draw on a user's medical records and other data collected by wearable devices, with their consent, to inform its responses.

Using electroencephalogram (EEG) technology, Neurable has developed a headset that records and deciphers brain activity.

The linked app compares data with the user's medical history to check for any deviation, a possible sign of a problem, said Alcaide.

"Apple Watch can pick up Parkinson's, but it can only pick it up once you have a tremor," Alcaide said. "Your brain has been fighting that Parkinson's for over 10 years."

With EEG technology, "you can pick these things up before you actually see physical symptoms of them. And this is just one example."

Detection before symptoms

Some people have reservations about the capabilities of such devices.

"I don't think that wearable EEG devices are reliable enough," said Anna Wexler, a University of Pennsylvania professor who studies consumer detection products, although she acknowledges that "AI has expanded the possibilities of these devices."

While Neurable's product cannot provide an actual diagnosis, it does offer a warning. It can also detect signs of depression and early development of Alzheimer's disease.

Neurable is working with the Ukrainian military to evaluate the mental health of soldiers on the front lines of the war with Russia, as well as former prisoners of war, in order to detect post-traumatic stress disorder (PTSD).

French startup NAOX meanwhile has developed EEG earbuds linked to a small box that can help patients with epilepsy.

Rather than detect seizures, which are "very rare," the device recognizes "spikes" -- quick, abnormal electrical shocks in the brain that are "much more difficult to see," said NAOX's chief of innovation Marc Vaillaud, a doctor by training.

NAOX's device -- which has been cleared by the US Food and Drug Administration -- is designed to be worn at night, to track several hours of data at a time.

The company is working with the Rothschild and Lariboisiere hospitals in Paris to try to better understand the links between these brain "spikes" and Alzheimer's disease, which have been raised in scientific papers.

Advances in AI and technology in general have paved the way for the miniaturization of cheaper detection devices -- a far cry from the heavy machinery once seen in medical offices and hospitals.

IriHealth is preparing to launch, for only about $50, a small smartphone extension that would scan a user's iris.

The gadget relies on iridology, a technique by which iris colors and markings are believed to reveal information about a person's health, but which is generally considered scientifically unreliable.

But the founders of IriHealth -- a spin-off of biometrics specialist IriTech -- are convinced that their device can be effective in detecting anomalies in the colon, and potentially the lungs or the liver.

Company spokesman Tommy Phan said IriHealth had found its device to be 81 percent accurate among patients who already have been diagnosed with colon cancer.



WWF: Populations of Wild Species Fell by an Average of 73% from 1970 to 2022

FILE PHOTO: A giraffe and zebras walk at a water point at the Amboseli National Park as authorities investigate the deaths of 18 elephants in Kenya's Amboseli ecosystem, in Kajiado County, Kenya,  August 26, 2026. REUTERS/Monicah Mwangi/File Photo
FILE PHOTO: A giraffe and zebras walk at a water point at the Amboseli National Park as authorities investigate the deaths of 18 elephants in Kenya's Amboseli ecosystem, in Kajiado County, Kenya, August 26, 2026. REUTERS/Monicah Mwangi/File Photo
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WWF: Populations of Wild Species Fell by an Average of 73% from 1970 to 2022

FILE PHOTO: A giraffe and zebras walk at a water point at the Amboseli National Park as authorities investigate the deaths of 18 elephants in Kenya's Amboseli ecosystem, in Kajiado County, Kenya,  August 26, 2026. REUTERS/Monicah Mwangi/File Photo
FILE PHOTO: A giraffe and zebras walk at a water point at the Amboseli National Park as authorities investigate the deaths of 18 elephants in Kenya's Amboseli ecosystem, in Kajiado County, Kenya, August 26, 2026. REUTERS/Monicah Mwangi/File Photo

Nearly 6,000 monitored vertebrate species across more than 35,000 populations declined by an average of 73% from 1970 to 2022, the World Wide Fund for Nature said in its latest Living Planet Report published on Thursday.

The Living Planet Index, managed by the Zoological Society of London and WWF, monitored a total of 35,803 populations covering 5,790 different species of mammals, birds, reptiles, amphibians and fish over the 52-year period.

The 2026 Living Planet Report estimates that overall populations fell by an average of around 2.5% per year over the period, Reuters reported.

"Monitored global populations continue to decline ⁠on average with no ⁠evidence yet of that global recovery," said Andrew Terry, chief conservation officer at ZSL.

The average rate of decline across the monitored populations does not represent a headcount of the total number of animals lost from 1970 to 2022, and the number is especially sensitive to changes in already small ⁠populations.

Monitored freshwater species saw an average decline of 85%, while terrestrial species fell 69% and marine species 59%, the index showed.

The steepest average population declines were in South America, at 95%, with Africa also experiencing losses of 80% from 1970 to 2022.

The 2026 Living Planet report incorporated an additional 295 species and 967 populations across a longer time series compared to the last report in 2024.

The additional data "reinforces our confidence in the continued decline in biodiversity," Terry told ⁠a briefing.

⁠Habitat loss and degradation were the most frequently reported threat, but wildlife populations are also at risk from overexploitation, climate change, pollution, invasive species and disease, the report said.

"Amid these steep declines, there are grounds for hope, rooted in evidence. Wildlife populations are under pressure but recovery is in reach," said Kirsten Schuijt, WWF's director general.

Targeted conservation efforts have enabled populations of some species to recover, including tigers, Atlantic and Pacific bluefin tuna, southern African elephants and green sea turtles.

Alongside conservation efforts, changes in the energy, food and finance systems are required to halt nature loss, Schuijt said.


A 194-year-old Tortoise, World's Oldest Land Animal, May Hold Clues to Longer Life

Tortoise named Jonathan, a giant tortoise believed to be the world's oldest known living land animal, stands in front of Plantation House, in St Paul on the South Atlantic island of St Helena, January 6, 2013.  Joe Hollins/Handout via REUTERS
Tortoise named Jonathan, a giant tortoise believed to be the world's oldest known living land animal, stands in front of Plantation House, in St Paul on the South Atlantic island of St Helena, January 6, 2013. Joe Hollins/Handout via REUTERS
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A 194-year-old Tortoise, World's Oldest Land Animal, May Hold Clues to Longer Life

Tortoise named Jonathan, a giant tortoise believed to be the world's oldest known living land animal, stands in front of Plantation House, in St Paul on the South Atlantic island of St Helena, January 6, 2013.  Joe Hollins/Handout via REUTERS
Tortoise named Jonathan, a giant tortoise believed to be the world's oldest known living land animal, stands in front of Plantation House, in St Paul on the South Atlantic island of St Helena, January 6, 2013. Joe Hollins/Handout via REUTERS

The world's oldest-known terrestrial animal, an Aldabra giant tortoise named Jonathan and estimated to be about 194 years old, may owe his extraordinary longevity to a combination of genetic traits and an ability to keep key cellular systems functioning in a more youthful way, according to scientists.

Members of this species are known to live more than 100 years, but Jonathan has far exceeded that. Brought to the remote South Atlantic island of St Helena as a fully grown animal in 1882, likely from the Aldabra Atoll or the Granitic Seychelles, the tortoise now resides in a paddock at Plantation House, the governor's residence.

"Other Aldabra tortoises have been claimed to have lived as long as Jonathan, but he has the most documentary evidence supporting his age," said Benjamin Vaisvil, a researcher affiliated with the organization Kallel and co-lead author of the study published on Wednesday in the journal Science Advances.

Scientists have studied Jonathan to explore the secrets of the animal's amazing longevity, sequencing his genome and analyzing his epigenome — the chemical markers that control which genes switch on and off.

"We found changes in Jonathan's genome in pathways associated with longevity, like DNA repair, mitochondrial function, insulin regulation and telomere function," ⁠Reuters quoted Vaisvil as saying.

Mitochondria are structures ⁠considered the powerhouse of a cell. Insulin is a hormone that helps regulate levels of blood sugar by letting it enter the body's cells for energy. Telomeres are protective caps at the ends of chromosomes, structures that carry genetic information inside cell nuclei.

Researchers compared Jonathan's epigenome with four other Aldabra tortoises, ranging from juveniles to older adults. While pretending to feed Jonathan, they waited until he began biting the air, then wedged his mouth open with a gloved hand and scraped under his tongue with a specialized kit. St Helena officials restrict blood draws to prevent infection risks.

To explain the finding, Vaisvil compared the genome to a cookbook and the epigenome to handwritten notes in the margins.

"As the cookbook ages, those notes become ⁠more difficult to read clearly. We can think of that as methylation entropy," Vaisvil said, referring to a metric for disorder in a certain biochemical process.

Most of the notes in Jonathan's "cookbook" look very old. But in certain regions, stretches of DNA that act as switches controlling whether genes are turned on or off, Jonathan's methylation entropy was lower than that of every tortoise studied except a 5-year-old juvenile. These regions controlled genes that influence longevity.

The researchers identified 287 genes with variants unique to Jonathan, including some linked to tumor suppression and DNA repair. The tortoise also carries extra copies of a gene that encodes a protein that hunts down ageing and cancerous cells.

When younger, Jonathan was known for mischievous antics including overturning chairs and lying on croquet balls, according to the tortoise's longtime veterinarian and study co-author Joe Hollins. Cataracts have since left him mostly blind. Hollins describes Jonathan today as "a gentle giant."

Determining how long giant tortoises can live is challenging because reliable historical records are scarce and many outlive researchers. Record-keeping before the 20th century also was problematic. While a young tortoise's age can be estimated from growth ⁠rings on the plates that form ⁠the animal's shell, ascertaining the age of adults is more difficult.

The new study involved only one exceptionally old tortoise, making it hard to determine whether the traits identified are unique to Jonathan or common among long-lived tortoises.

"We cannot say for certain that what we found is the reason for his longevity," Vaisvil said.

Environmental factors also may have contributed. Jonathan lives on a tropical island, with an optimal diet carefully managed by trained veterinarians.

The research findings broadly match patterns documented in studies of exceptionally long-lived people, suggesting that some mechanisms of aging may be shared across species.

Vaisvil noted that a recent study of a 117-year-old woman found unusually efficient mitochondrial function, echoing findings in some of Jonathan's regions.

Despite his age, Jonathan retains a voracious appetite, Hollins said, lifting his head and stretching out his long neck when the veterinarian calls out his name.

"I know he knows me, knows my voice and my handling, and I also know it isn't love on his part but a recognition of the arrival of a feast," Hollins said. "And yet I, of course, don't mind. I have a huge affection for him."

"He is a remarkable symbol. Icon, I know, is an overused word, but Guinness World Records has just given him 'icon' status this year," Hollins said.

Beloved by island residents, Jonathan has lived through world wars and the rise and fall of empires.

"He is symbolic of resilience, longevity, endurance, a persistent presence throughout huge historic events," Hollins said.


Barn Owls, Bees, Puffins and Hedgehogs to Feature on UK Banknotes

FILE PHOTO: Mock-ups of banknotes featuring wildlife are shown, after the public chose that theme from the suggested options of a consultation held by the Bank of England for the next series of banknote designs, in this handout image obtained by Reuters on March 10, 2026. Bank of England/Handout via REUTERS
FILE PHOTO: Mock-ups of banknotes featuring wildlife are shown, after the public chose that theme from the suggested options of a consultation held by the Bank of England for the next series of banknote designs, in this handout image obtained by Reuters on March 10, 2026. Bank of England/Handout via REUTERS
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Barn Owls, Bees, Puffins and Hedgehogs to Feature on UK Banknotes

FILE PHOTO: Mock-ups of banknotes featuring wildlife are shown, after the public chose that theme from the suggested options of a consultation held by the Bank of England for the next series of banknote designs, in this handout image obtained by Reuters on March 10, 2026. Bank of England/Handout via REUTERS
FILE PHOTO: Mock-ups of banknotes featuring wildlife are shown, after the public chose that theme from the suggested options of a consultation held by the Bank of England for the next series of banknote designs, in this handout image obtained by Reuters on March 10, 2026. Bank of England/Handout via REUTERS

Barn owls, bumblebees, puffins and hedgehogs will feature on new Bank of England banknotes over the coming years, replacing World War Two leader Winston Churchill and other historic figures, the Bank of England said on Thursday.

The BoE's decision in March to no longer feature famous Britons on future banknotes, in favor of native wildlife, dismayed politicians across the political spectrum and prompted speculation that the central bank wanted to avoid controversies around historic figures.

The BoE said the change would make its banknotes ⁠more distinctive and harder ⁠to counterfeit, and followed a public consultation where people had been invited to choose between different categories of images.

Almost 500,000 people voted on a selection of 18 animals released by the central bank in June.

The buff-tailed bumblebee was the most popular creature ⁠on the shortlist, followed by the barn owl and the European hedgehog. Red foxes and common kingfishers received more votes than the Atlantic puffin, which the BoE selected to ensure a marine animal was on the list.

"I am delighted that nearly half a million people responded to our wildlife imagery consultation, showing that cash still matters," Reuters quoted BoE Chief Cashier Victoria Cleland as saying.

Cash usage has fallen steeply in Britain in recent years, accelerated by ⁠the COVID-19 ⁠pandemic which led to almost all retailers accepting contactless card and smartphone payments.

Under 10% of payments were made by cash in 2024, but trade body UK Finance said it expected the decline to level off as a small percentage of Britons strongly preferred to use cash.

The new banknotes will continue to feature the monarch. The £5 Churchill note, issued in 2016, is the first due to be replaced, followed by the £10 with novelist Jane Austen, £20 with artist JMW Turner and £50 with mathematician Alan Turing.