Israeli Prime Minister Benjamin Netanyahu said Iran must not be allowed to gain nuclear arms and urged Israelis to "stand together" after Israel and the United States launched strikes against Iran on Saturday.
"This murderous terrorist regime must not be allowed to arm itself with nuclear weapons that would enable it to threaten all of humanity," Netanyahu said in a video statement.
"Together we will stand, together we will fight and together we will ensure the eternity of Israel," he added.
Netanyahu said that the joint US-Israeli attack "will create the conditions for the brave Iranian people to take their destiny into their own hands."
"The time has come for all sections of the people in Iran ... to remove the yoke of tyranny from (the regime) and bring a free and peace-loving Iran," Netanyahu said in a statement.
The attack follows a 12-day air war in June between Israel and Iran and repeated US-Israeli warnings that they would strike again if Iran pressed ahead with its nuclear and ballistic missile programs.
An Israeli defense official said the operation had been planned for months in coordination with Washington, and that the launch date was decided weeks ago.