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BioNTech Produces 10 Times More Antibodies than China's Sinovac: Study

Pfizer said an early peek at its vaccine data suggests the shots may be 90% effective at preventing COVID-19. (Reuters)
Pfizer said an early peek at its vaccine data suggests the shots may be 90% effective at preventing COVID-19. (Reuters)
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BioNTech Produces 10 Times More Antibodies than China's Sinovac: Study

Pfizer said an early peek at its vaccine data suggests the shots may be 90% effective at preventing COVID-19. (Reuters)
Pfizer said an early peek at its vaccine data suggests the shots may be 90% effective at preventing COVID-19. (Reuters)

People who received BioNTech's coronavirus vaccine had ten times the amount of antibodies than those given China's Sinovac, a Hong Kong study has shown, adding to growing data on different jabs' effectiveness.

The University of Hong Kong (HKU) research, based on a study of 1,442 healthcare workers, was published in Lancet Microbe on Thursday.

Researchers said antibodies are not the only measure of a vaccine's success at fighting a particular disease.

But they warned that "the difference in concentrations of neutralizing antibodies identified in our study could translate into substantial differences in vaccine effectiveness".

Those who received Sinovac had "similar or lower" levels of antibodies to those seen in patients who caught and successfully fought off the disease.

The study adds to the growing body of evidence that vaccines using pioneering mRNA technology -- such as BioNTech and Moderna -- offer better protection against the coronavirus and its variants that those developed by more traditional methods such as using inactivated virus parts.

Traditional vaccines are cheaper to produce and less complicated to transport and store, making them a vital tool for fighting the pandemic in less wealthy countries.

- 'Many lives still saved' -
Epidemiologist Ben Cowling, one of the report's authors, said people should still get vaccinated with Sinovac if there was no other option because some protection was always better than none.

"Don't let the perfect be the enemy of the good," he told AFP.

"It is clearly better to go and get vaccinated with an inactivated vaccine than to wait and not get vaccinated," he added.

"Many, many lives have been saved by the inactivated vaccine."

The researchers said their data suggested "alternative strategies" such as earlier booster shots might be needed to increase protection for those who have received Sinovac.

Cowling said when to give booster shots would be the next phase of their ongoing studies.

"The priority would be boosters for people who received Sinovac while boosters for people who initially received BioNTech might not be so urgent," he said.

- Politics -
Hong Kong has been a world leader in studying coronaviruses ever since a SARS outbreak which began in southern China swept through the city in 2003.

The city currently offers both German-made BioNTech shots and Sinovac.

Despite ample supplies, take-up has been slow, with only 28 percent of the city's 7.5 million residents fully vaccinated with two shots.

So far some 2.6 million BioNTech doses have been administered compared to 1.8 million Sinovac shots.

The rollout has been caught up in Hong Kong's febrile politics, as China cracks down on dissent in the city in response to huge and often violent democracy protests two years ago.

At the start of the vaccination campaign Hong Kong's pro-Beijing leaders very visibly and near unanimously opted for Sinovac.

One doctor's clinic that recommended BioNTech over Sinovac was kicked out of the city's vaccination program.

Many of the city's leading epidemiologists have gone with BioNTech, and said publicly that it is their preferred shot.

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Hearing Aids Can Seem Like a Big Step. This NYC Ballet Principal Dancer Doesn't Regret Taking It

Sara Mearns, principal dancer at New York City Ballet, wearing hearing aids on March 17, 2026, in New York. (AP Photo/Shelby Lum)
Sara Mearns, principal dancer at New York City Ballet, wearing hearing aids on March 17, 2026, in New York. (AP Photo/Shelby Lum)
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Hearing Aids Can Seem Like a Big Step. This NYC Ballet Principal Dancer Doesn't Regret Taking It

Sara Mearns, principal dancer at New York City Ballet, wearing hearing aids on March 17, 2026, in New York. (AP Photo/Shelby Lum)
Sara Mearns, principal dancer at New York City Ballet, wearing hearing aids on March 17, 2026, in New York. (AP Photo/Shelby Lum)

Sara Mearns was missing her cues. She couldn't hear what her dance partner was saying from across the studio. She was late for her entrances because the music sounded too soft.

Without telling anyone, she finally made an appointment to get her hearing checked.

Mearns learned that she had hearing loss. After years of isolation, she got the tools to make sense of a world that had gotten muffled.

Now, she's one of the first dancers with the New York City Ballet to wear hearing aids during performances.

“I feel like it's a whole new chapter of my life,” Mearns, 40, said in an interview with the AP.

While hearing loss is common in older adults, it can happen at any age and can be caused by things like nerve damage, infection or head trauma. For Mearns, it may have been a blend of factors including genetics, medical conditions and exposure to loud noise.

Signs and symptoms of hearing loss According to the National Institutes of Health, less than a fifth of American adults aged 20 to 69 who could benefit from wearing hearing aids have ever used them. That's due to lack of access, shame or embarrassment and just not knowing the symptoms.

“Hearing loss is often not detected by the person because what they can't hear, they don't know,” said Dr. Anil Lalwani, a hearing expert with Columbia University Irving Medical Center.

Still, “there are a lot of symptoms of hearing loss that are not hearing less,” said Dr. Maura Cosetti with Mount Sinai’s New York Eye and Ear Infirmary.

One thing to look out for is saying “what” more often, and not being able to hear friends and family in noisy settings like restaurants. Other symptoms include ringing, a sensation like something is stuck in the ears or conversations sounding muffled.

During the COVID-19 pandemic, Mearns couldn't hear conversations when people were wearing masks.

“I realized that I was reading everybody’s lips to understand what they were saying,” she said.

If experiencing hearing loss, you have options Experts say to let a doctor know if you think you may be experiencing symptoms of hearing loss. They can help you connect with an audiologist or an ear, nose and throat specialist to get a hearing test.

Cosetti with Mount Sinai said the Mimi Hearing Test app can be useful resource to get a sense of your hearing. Seeing a professional is the best way to figure out what's actually going on — like whether your ears are just plugged up with wax or fluid.

Hearing aids fine-tune the sound signal that enters the brain, enhancing speech while lowering background noise. They can be expensive, but many are now available over the counter. Some Apple AirPods also can be used as hearing aids.

For more severe forms of hearing loss, doctors may recommend a device called a cochlear implant, which converts sounds into electrical signals that are sent to the brain. These include a surgically inserted component and can take months to get used to.

Hearing aids are an adjustment, but can be worth it Mearns initially felt embarrassed to step into the booth for her hearing test, knowing she wouldn't be able to hear all the words. Her audiologist, Marta Gielarowiec, helped her understand what she was missing and guided her to appropriate hearing aids.

“It's definitely not a one size fits all. There is a lot of adjustment, tuning and calibration involved,” said Gielarowiec, who runs a practice in New York. “Overall, the goal is to maximize the hearing that’s left.”

Addressing hearing loss can help boost mental health, improve communication and slow cognitive decline for people at high risk of dementia.

When Mearns walked out of her audiologist's office wearing her aids for the first time, she felt overwhelmed. She could hear the pattering of shoes on the ground, the chirping of birds across the street and the billowing of a flag a block behind her. Returning to her dressing room, she cried.

She can now hear the full might of the orchestra when she performs — and take phone calls in her ears.

The life she was living before, she said, was exhausting. At the end of every day she was spent from the strain of asking people to repeat themselves and missing out on conversations and the punch lines of jokes.

“I don’t want people to feel what I felt, where I was embarrassed and I was quiet about it,” she said. “Because now that I’m on the other side, I’m so happy.”

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What Effect do Painkillers Have on Blood Pressure?

A man measures his blood pressure using a wrist device (Pixabay)
A man measures his blood pressure using a wrist device (Pixabay)
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What Effect do Painkillers Have on Blood Pressure?

A man measures his blood pressure using a wrist device (Pixabay)
A man measures his blood pressure using a wrist device (Pixabay)

People with high blood pressure should exercise caution when using over-the-counter painkillers. No medication is entirely risk-free.

Anti-inflammatory painkillers such as ibuprofen can raise blood pressure, increasing the risk of heart attack or stroke.

Patients with hypertension are advised to avoid them. Paracetamol is considered an alternative, but it may also raise blood pressure. It is important to understand this, as continued use could increase the risk of heart attack or stroke.

Blood pressure, heart attacks and painkillers

In 2004, Merck & Co. withdrew rofecoxib (Vioxx) from the market after it was found to increase the risk of heart attacks and strokes. This prompted a broader review of similar drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs).

These widely used medications relieve pain, reduce inflammation and lower fever. They include over-the-counter drugs such as aspirin, ibuprofen (Advil, Motrin) and naproxen (Aleve), as well as prescription drugs such as celecoxib (Celebrex), according to Harvard Medical School.

It soon became suspected that all NSAIDs, except aspirin, increase the risk of heart attack. This led the US Food and Drug Administration to require warning labels about this side effect on all NSAIDs. Earlier this year, the agency reviewed whether to ease the warning on naproxen after analysis suggested a lower heart risk compared with other NSAIDs. However, an advisory panel voted against changing the label, so the warning remains in place for all NSAIDs.

Tips for using painkillers

- Use the safest option

Unless advised by a doctor, avoid over-the-counter painkillers such as ibuprofen, naproxen sodium or ketoprofen. Instead, use options less likely to raise blood pressure, such as aspirin or paracetamol.

- Follow directions

Use medication as instructed and follow recommended dosages. Most painkillers should not be used for more than 10 days. If pain persists, consult a doctor, according to WebMD.

- Monitor blood pressure regularly

This is important for anyone with hypertension, especially when using medications that may raise blood pressure.

- Be aware of drug interactions

Many medications used to treat common conditions can interact with over-the-counter painkillers. NSAIDs, for example, may interfere with commonly used blood pressure medications.

Dr Nieca Goldberg, a cardiologist and spokesperson for the American Heart Association, said taking aspirin with prescribed blood thinners such as Eliquis, Coumadin, Plavix and Xarelto may be risky. Patients taking prescription medications for blood pressure or other conditions should consult a doctor about which over-the-counter drugs to avoid.

- Read the medication leaflet

Review side effects and potential drug interactions listed with the medication.

- Check all ingredients

Painkillers such as aspirin, paracetamol and ibuprofen may be present in unexpected products, including cold or heartburn medications.

- Inform your doctor of all medications and supplements

Drug interactions are a real risk. Healthcare providers need to know all medications being taken, including over-the-counter drugs, herbal remedies and vitamins.

Goldberg added that patients should bring a list of all medications and supplements they take to their doctor, as this could be life-saving.

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How Does Mental Health Affect Diabetes Patients?

Depression causes fatigue and lack of motivation for self-care (File- Reuters)
Depression causes fatigue and lack of motivation for self-care (File- Reuters)
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How Does Mental Health Affect Diabetes Patients?

Depression causes fatigue and lack of motivation for self-care (File- Reuters)
Depression causes fatigue and lack of motivation for self-care (File- Reuters)

Mental health has a direct and bidirectional impact on people with diabetes. Psychological stress such as loneliness, anxiety and depression can raise blood sugar levels through hormonal effects, while also reducing motivation for self-care.

According to Healthline, estimates suggest that about 10% of patients experience depression and 25% experience mood fluctuations, negatively affecting adherence to treatment and glucose monitoring.

Diabetes and loneliness

Loneliness is closely linked to an increased risk of developing type 2 diabetes and to worsening health outcomes in those who already have the condition.

Chronic loneliness triggers stress hormones such as cortisol, increasing insulin resistance and raising blood sugar levels. It may also lead to neglect of self-care and unhealthy lifestyle habits.

Relationship between loneliness and diabetes:

Studies suggest loneliness and social isolation may increase the risk of developing type 2 diabetes by up to 32%.

Higher levels of loneliness have been observed among patients with chronic complications such as retinopathy or neuropathy.

Loneliness activates the body’s stress response on a daily basis, increasing cortisol and disrupting blood sugar regulation.

Studies indicate loneliness may raise the risk of heart disease in people with diabetes by up to 26%.

People experiencing loneliness are more likely to be physically inactive, smoke, and follow unhealthy diets.

Diabetes, anxiety and depression

Anxiety and depression have a two-way relationship with diabetes. Depression increases the risk of developing type 2 diabetes, and people with diabetes are more likely to experience depression, which negatively affects blood sugar control.

Relationship between diabetes, depression and anxiety:

People with diabetes are two to three times more likely to develop depression.

Depression risk increases in both type 1 and type 2 diabetes, reducing quality of life.

Depression leads to fatigue and low motivation for self-care, raising blood sugar levels.

The daily burden of managing diabetes may lead to “diabetes distress,” a mix of frustration and anxiety.

Managing stress to control diabetes

Psychological support: speaking with a doctor or mental health specialist is essential.

Integrated care: combining mental health care with diabetes management.

Lifestyle measures: regular exercise, healthy eating, and adherence to medication schedules.

Physical activity: helps reduce stress hormones and improve insulin sensitivity.

Relaxation techniques: yoga, meditation and deep breathing.

Adequate sleep: sleep deprivation increases cortisol levels.

Continuous monitoring: use of continuous glucose monitoring devices.