Makeshift Captagon Labs Emerge in Syria from Rubble of Assad’s Narcotics Trade

Asharq Al-Awsat examines the impact the drug has and continues to have on the country.

Syria's new authorities burn hundreds of tons of Captagon pills and bags of hashish at the headquarters of the Fourth Division in Damascus. (EPA)
Syria's new authorities burn hundreds of tons of Captagon pills and bags of hashish at the headquarters of the Fourth Division in Damascus. (EPA)
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Makeshift Captagon Labs Emerge in Syria from Rubble of Assad’s Narcotics Trade

Syria's new authorities burn hundreds of tons of Captagon pills and bags of hashish at the headquarters of the Fourth Division in Damascus. (EPA)
Syria's new authorities burn hundreds of tons of Captagon pills and bags of hashish at the headquarters of the Fourth Division in Damascus. (EPA)

Ahmed el-Jouri

 

Syria has not only endured a war that shattered its cities, but also a quieter conflict—one that devours lives long before bodies fall. Amid the charred ruins of burned-out neighborhoods, an entire generation has grown up under the grip of a cheap pill originally intended for export but now flooding the local market.

The story began when the former Syrian regime transformed Captagon—a synthetic stimulant made from amphetamine and theophylline—into a lucrative war currency.

Once a controlled substance, it soon became a torrent surging through the country's alleys and streets, robbing youths of their futures and turning dreams into nightmares.

By 2020, the crisis had deepened. The price of a single Captagon pill plummeted from $1.50 to just five cents—cheaper than a cup of tea.

The drop reflected a cascade of events: the enforcement of the Caesar Act sanctions, sweeping sanctions targeting the Assad government, Lebanon's economic and banking collapse in late 2019, restrictions on dollar transactions and withdrawals from Lebanon, and tighter control over land borders that slightly curbed smuggling.

This Asharq Al-Awsat investigation, drawing on field visits to areas of post-Assad Syria and interviews with pharmacists and doctors in Amman and Erbil, retraces the production pipeline of Captagon.

It also features testimonies from addicts and their families, painting a stark portrait of a drug that fuels despair in a nation already exhausted by war.

A member of the Syrian security forces at a Captagon factory in Douma near Damascus on December 13. (AP)

In the shadows: Captagon addiction grips Syria's youth

In the crumbling streets of Damascus, where tangled electric wires dangle like specters above weary passersby, a toxic trade thrives under innocent names—“energy pills”, “happiness tablets” and others depending on the dealer. But behind the playful labels lies a systematic crisis. Syria's youth are not falling to addiction by chance—they are being consumed by design.

According to the International Labor Organization, 39.2% of working-age Syrians (15 and older) were unemployed in 2023. But statistics say little about how people like Ahmed, 19, spend their days.

Slumped on a crumbling curb in Damascus' Rukn al-Din district, Ahmed stares at his tattered shoes as a nearby dealer leans in: “This pill will make you a man... you'll work like a horse without feeling tired.”

Ahmed didn't know that the “man” he was promised would become enslaved to a handful of blue pills. The long hours at a bombed-out workshop turned into a nightmare only numbed by more doses.

His story is far from unique. It echoes across Syria like a shared curse in a land battered by war and poverty. In this darkness, Captagon glimmers like a false shooting star. Sources recount how the pill knocks down young people one after another, like dominoes—girls included.

Even the dream of escape has become part of the tragedy. Some sell family land to fund a risky boat journey out of the country. One man made it only as far as a Turkish prison—addicted, penniless, landless, and with no future.

This investigation collected over a dozen testimonies from across Syria—either directly from addicts or their families—offering a window into a drug crisis that has taken a darker turn since the fall of Assad's regime.

What was once a tightly controlled trade, reliant on pharmaceutical infrastructure and exports while feeding a growing domestic market, has devolved into a chaotic, deadly business claiming more lives through overdoses and despair.

Yasser, 17, from Aleppo, was kicked out of his family home and now lives in a basement room owned by his uncle-in-law.

“My friends used to laugh when they took the pills,” Yasser told Asharq Al-Awsat.

“They told me it felt like being the hero in a video game. I tried them to prove I was brave like them. Now, I wander the streets like a ghost. I hear my mother's voice haunting me. On cold nights, I sneak back to our house, touch the locked door and imagine a shell falling on me... maybe death would offer me a forgiveness I don't deserve,” he added.

In the northeastern city of Hasaka, Ali, 22, from Deir Ezzor, spoke after a grueling day of physical labor. “One day, I carried sacks of flour on my back for 10 straight hours,” he recalled.

“My boss was watching, then tossed me a pill and said, 'Take this—it'll make your back like iron.' Now, my back carries more than weight... the heaviest burden is what I see in my children's eyes. When I get home, I pretend to sleep so they won't come near me. I hear them whisper, 'Papa sleeps like he's dead.'”

Mohammad Abu Youssef, 45, rubs his cracked hands and gazes at a photo of his eldest son.

“I sold my health, worked myself to the bone just to pay his school fees. But Captagon stole him from me,” he said.

“When I found him trembling like a leaf in the corner, I screamed, 'Why didn't you die in the bombing?!' I tried sending him to Europe with smugglers, but he fled the truck halfway and returned months later—his eyes are just two black voids. Now, I've locked him in the house. I buy the pills for him myself and pray every night that God takes him.”

Captagon pills concealed in fake fruit found inside a factory in Douma east of Damascus. (EPA)

No rehab, no way out: Syria's addicts face slow death

In a country ravaged by war and addiction, the absence of rehabilitation centers is proving fatal for many. Without treatment options, a growing number of Syrians are left to spiral deeper into dependency—with no support, no shelter, and no escape.

Dr. Rawan al-Hussein, who requested using an alias for safety reasons, works with a branch of the health directorate and also consults for a non-governmental organization focused on addiction cases. Each day, she sifts through piles of case files, trying to salvage what's left of shattered lives.

“Just last week, a frail young man came to me carrying his infant daughter,” she recalled.

“He said, 'Take her before I sell her for pills. I don't even have a bed to put her in.'”

With rehab facilities scarce or nonexistent in many areas, stories like his are becoming tragically common—leaving medical workers overwhelmed and addicts trapped in a slow-motion collapse.

Al-Hussein exhaled deeply as she gathers water-damaged papers from her desk.

“International organizations send us boxes of medicine without assessing our needs,” she said. “Our youth are dying because the toxins are already in their blood. What are we supposed to do with bandages for wounds no one can see?”

The real tragedy, she explained, lies not just in the spread of addiction, but in the absence of mental health and rehabilitation services.

Staff working in Syria with the UNHCR and the World Health Organization told Asharq Al-Awsat that as of February 2025, there were no more than 10 specialized rehabilitation centers across the country, while the need is estimated at over 150.

With more than 70% of health facilities damaged or destroyed by war, accessing emergency care or psychiatric treatment has become nearly impossible.

“Even the programs that do exist are struggling,” al-Hussein added. “They rely heavily on volunteers and lack basic psychiatric medications.”

But the crisis runs deeper than infrastructure. Stigma, too, is a powerful barrier. “In Daraa, for example, residents rejected plans to open a rehab center out of fear it would tarnish the area's reputation,” a local organization told Asharq Al-Awsat.

Caught between a crumbling healthcare system and a society that shuns them, Syria's addicts are left to fight a silent war with little hope of rescue.

Captagon after Assad: Makeshift labs and a generation being wiped out by doses

The fall of the Assad regime did not mark the end of Syria's suffering—instead, it ignited a new phase of chaos, more fragmented and deadly.

As state institutions collapsed during years of war, young people became easy prey to a cheap addiction. Now, the regime's toxic legacy is playing out in the shadows through a deadlier, more decentralized Captagon industry.

While the new authorities dismantled public-facing drug labs in the wake of Assad's downfall, they failed to anticipate what would come next: the splintering of production into informal workshops run by former smugglers and recovering addicts navigating a shattered economy.

The once-affordable pill that had flooded the streets is now scarcer—and more expensive—driving many addicts to work inside the very workshops that sustain their addiction.

These makeshift labs operate with no safety standards, mixing dangerous chemicals by hand, without protective gear, and relying on improvised recipes that often push the drug's potency to lethal extremes.

In this post-Assad vacuum, Syria's Captagon trade has not disappeared—it has mutated, dragging a generation deeper into a cycle of desperation, exploitation, and overdose.

In the immediate aftermath of Assad's fall, Syria's new leadership launched a sweeping military and security campaign aimed at dismantling the country's Captagon empire—a key source of funding for the ousted regime.

The crackdown succeeded in destroying dozens of large-scale production facilities in the rural outskirts of Homs and Damascus. But what seemed like a victory soon spiraled into a deeper crisis.

With the collapse of organized production, the price of a single Captagon pill soared—from just five cents to more than $1.50, according to pharmacists and users interviewed by Asharq Al-Awsat.

Primitive material used to manufacture Captagon in the village of Hawik. (Asharq Al-Awsat)

The price surge has pushed many addicts into a state of desperation, willing to pay or do anything for a fix. It's a Russian doll of catastrophe: inside every crisis, a smaller one waits. The fall of Assad did not dismantle the machinery of death—it merely scattered it into thousands of dangerous fragments.

The addicts once hooked on the “cheap high” of mass-produced Captagon are now trapped in a darker spiral: counterfeit pills from unregulated workshops, mixed with unknown chemicals, sold on the black market.

To stave off withdrawal, users are turning to theft or joining smuggling rings. Families who once believed that regime change would bring their sons and daughters back from the brink have instead watched as they became statistics—new entries in the growing toll of addiction and overdose.

What began as a crackdown has, for many Syrians, morphed into a new chapter of the same tragedy—only now, it's less visible and harder to stop.

Captagon under Assad: A state-engineered drug empire disguised as pharma

Under the Assad regime, Captagon production was far from a rogue operation. It was a state-run enterprise cloaked in the legitimacy of Syria's once-thriving pharmaceutical sector.

Before the war, Syria boasted one of the most advanced pharmaceutical industries in the Middle East. The regime exploited that infrastructure to manufacture synthetic drugs on a large scale.

Licensed factories in Aleppo and Damascus—equipped with modern technology—became the backbone of a sophisticated narcotics operation. Inside, chemists and pharmacists engineered carefully calibrated formulas designed to hook users without causing immediate deaths.

Three former pharmacists who worked in separate Syrian pharmaceutical firms told Asharq Al-Awsat that official state laboratories were covertly used to develop these drug blends.

At times, authorities would shut down or confiscate equipment from legitimate factories under false pretenses—creating space for Captagon experts to refine new chemical compositions.

A chemical engineer who worked in a factory in Al-Kiswah, south of Damascus, said the effort was supported by foreign expertise.

“Iranian and Indian specialists were brought in to help perfect the formula,” the source revealed.

“There were strict protocols in place. The regime wanted addictive pills without scandals. That's why Syrian Captagon became the most sought-after on the market.”

Lighter versions of the drug were even rebranded and sold as “party pills”, offering users a temporary high and masking the addiction beneath.

Assad's narcotics machine wasn't just a revenue stream. It was a calculated instrument of control, designed to addict both domestic users and foreign buyers while preserving plausible deniability.



What to Know about the Tensions between Iran and the US before Their Third Round of Talks

The flags of US and Iran are displayed in Muscat, Oman, 25 April 2025. Iran and US will hold third round of nuclear talks on 26 April 2025, in Muscat. (EPA)
The flags of US and Iran are displayed in Muscat, Oman, 25 April 2025. Iran and US will hold third round of nuclear talks on 26 April 2025, in Muscat. (EPA)
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What to Know about the Tensions between Iran and the US before Their Third Round of Talks

The flags of US and Iran are displayed in Muscat, Oman, 25 April 2025. Iran and US will hold third round of nuclear talks on 26 April 2025, in Muscat. (EPA)
The flags of US and Iran are displayed in Muscat, Oman, 25 April 2025. Iran and US will hold third round of nuclear talks on 26 April 2025, in Muscat. (EPA)

Iran and the United States will hold talks Saturday in Oman, their third round of negotiations over Tehran’s rapidly advancing nuclear program.

The talks follow a first round held in Muscat, Oman, where the two sides spoke face to face. They then met again in Rome last weekend before this scheduled meeting again in Muscat.

Trump has imposed new sanctions on Iran as part of his “maximum pressure” campaign targeting the country. He has repeatedly suggested military action against Iran remained a possibility, while emphasizing he still believed a new deal could be reached by writing a letter to Iran’s 85-year-old Supreme Leader Ali Khamenei to jumpstart these talks.

Khamenei has warned Iran would respond to any attack with an attack of its own.

Here’s what to know about the letter, Iran’s nuclear program and the tensions that have stalked relations between Tehran and Washington since the 1979 revolution.

Why did Trump write the letter? Trump dispatched the letter to Khamenei on March 5, then gave a television interview the next day in which he acknowledged sending it. He said: “I’ve written them a letter saying, ‘I hope you’re going to negotiate because if we have to go in militarily, it’s going to be a terrible thing.’”

Since returning to the White House, the president has been pushing for talks while ratcheting up sanctions and suggesting a military strike by Israel or the US could target Iranian nuclear sites.

A previous letter from Trump during his first term drew an angry retort from the supreme leader.

But Trump’s letters to North Korean leader Kim Jong Un in his first term led to face-to-face meetings, though no deals to limit Pyongyang’s atomic bombs and a missile program capable of reaching the continental US.

How did the first round go? Oman, a sultanate on the eastern edge of the Arabian Peninsula, hosted the first round of talks between Iranian Foreign Minister Abbas Araghchi and US Middle East envoy Steve Witkoff. The two men met face to face after indirect talks and immediately agreed to this second round in Rome.

Witkoff later made a television appearance in which he suggested 3.67% enrichment for Iran could be something the countries could agree on. But that’s exactly the terms set by the 2015 nuclear deal struck under US President Barack Obama, from which Trump unilaterally withdrew America.

Witkoff hours later issued a statement underlining something: “A deal with Iran will only be completed if it is a Trump deal.” Araghchi and Iranian officials have latched onto Witkoff’s comments in recent days as a sign that America was sending it mixed signals about the negotiations.

Yet the Rome talks ended up with the two sides agreeing to starting expert-level talks this Saturday. Analysts described that as a positive sign, though much likely remains to be agreed before reaching a tentative deal.

Why does Iran’s nuclear program worry the West? Iran has insisted for decades that its nuclear program is peaceful. However, its officials increasingly threaten to pursue a nuclear weapon. Iran now enriches uranium to near weapons-grade levels of 60%, the only country in the world without a nuclear weapons program to do so.

Under the original 2015 nuclear deal, Iran was allowed to enrich uranium up to 3.67% purity and to maintain a uranium stockpile of 300 kilograms (661 pounds). The last report by the International Atomic Energy Agency on Iran’s program put its stockpile at 8,294.4 kilograms (18,286 pounds) as it enriches a fraction of it to 60% purity.

US intelligence agencies assess that Iran has yet to begin a weapons program, but has “undertaken activities that better position it to produce a nuclear device, if it chooses to do so.”

Ali Larijani, an adviser to Iran’s supreme leader, has warned in a televised interview that his country has the capability to build nuclear weapons, but it is not pursuing it and has no problem with the International Atomic Energy Agency’s inspections. However, he said if the US or Israel were to attack Iran over the issue, the country would have no choice but to move toward nuclear weapon development.

“If you make a mistake regarding Iran’s nuclear issue, you will force Iran to take that path, because it must defend itself,” he said.

Why are relations so bad between Iran and the US? Iran was once one of the US’s top allies in the Middle East under Shah Mohammad Reza Pahlavi, who purchased American military weapons and allowed CIA technicians to run secret listening posts monitoring the neighboring Soviet Union. The CIA had fomented a 1953 coup that cemented the shah’s rule.

But in January 1979, the shah, fatally ill with cancer, fled Iran as mass demonstrations swelled against his rule. The revolution followed, led by Khomeini, and created Iran’s theocratic government.

Later that year, university students overran the US Embassy in Tehran, seeking the shah’s extradition and sparking the 444-day hostage crisis that saw diplomatic relations between Iran and the US severed. The Iran-Iraq war of the 1980s saw the US back Saddam Hussein. The “Tanker War” during that conflict saw the US launch a one-day assault that crippled Iran at sea, while the US later shot down an Iranian commercial airliner that the American military said it mistook for a warplane.

Iran and the US have see-sawed between enmity and grudging diplomacy in the years since, with relations peaking when Tehran made the 2015 nuclear deal with world powers. But Trump unilaterally withdrew America from the accord in 2018, sparking tensions in the Middle East that persist today.