A strike hit Beirut's southern suburbs on Monday, AFPTV footage showed, after Israel issued a warning for people in the Hezbollah stronghold to leave.
The strike is the first since Friday in the area, which is now largely deserted since Israel began frequent attacks against Hezbollah in early March.
AFPTV's live broadcast showed plumes of smoke rising from the southern suburbs.
Lebanon was pulled into the war in the Middle East when Hezbollah fired rockets at Israel on March 2 in solidarity with Tehran, two days after Iran was attacked by Israel and the United States. Hezbollah's attack prompted a new Israeli offensive against the group.
Israel has retaliated with wide-ranging air strikes on Lebanon, and Israeli forces are now advancing into numerous towns in southern Lebanon.
Israeli officials say they intend to set up a security zone extending 30 kilometers from the Israeli border to protect those living in northern Israel.