Israel Hits an Iranian Nuclear Research Facility, Says It’s Preparing for Possibly Long War

Rocket trails are seen in the sky above the Israeli coastal city of Netanya amid a fresh barrage of Iranian missile attacks on June 21, 2025. (AFP)
Rocket trails are seen in the sky above the Israeli coastal city of Netanya amid a fresh barrage of Iranian missile attacks on June 21, 2025. (AFP)
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Israel Hits an Iranian Nuclear Research Facility, Says It’s Preparing for Possibly Long War

Rocket trails are seen in the sky above the Israeli coastal city of Netanya amid a fresh barrage of Iranian missile attacks on June 21, 2025. (AFP)
Rocket trails are seen in the sky above the Israeli coastal city of Netanya amid a fresh barrage of Iranian missile attacks on June 21, 2025. (AFP)

Israel 's military said Saturday it struck an Iranian nuclear research facility overnight and killed three senior Iranian commanders in targeted attacks, while emphasizing it was preparing for the possibility of a lengthy war. 

Smoke rose from an area near a mountain in Isfahan, where Isfahan province’s deputy governor for security affairs, Akbar Salehi, confirmed the Israeli strikes damaged the facility but caused no casualties. 

The target was two centrifuge production sites, according to an Israeli military official speaking on condition of anonymity under army guidelines to brief reporters. It was the second attack on Isfahan, which was hit in the first 24 hours of the war as part of Israel's goal to destroy Iran's nuclear program. 

The International Atomic Energy Agency confirmed the latest attack. 

Iran launched a new wave of drones and missiles at Israel but there were no immediate reports of significant damage. The Magen David Adom rescue service said a drone hit a two-story building in northern Israel, with no casualties. 

The Israeli official called it a “small barrage” that was largely intercepted by Israel's defenses. The official estimated that Israel's military has taken out more than 50% of Iran's launchers. 

“We're making it harder for them to fire toward Israel,” he said. “Having said all that, I want to say the Iranian regime obviously still has capabilities.” 

The Israeli military’s chief spokesman, Brig. Gen. Effie Defrin, later said Chief of Staff Lt. Gen. Eyal Zamir told the army to be prepared for a “prolonged campaign." 

Iran says US military involvement would be ‘dangerous’  

US President Donald Trump is weighing active US military involvement in the war. On Saturday, Iranian Foreign Minister Abbas Araghchi said, “I think that it would be very, very dangerous for everyone.” He spoke on the sidelines of an Organization of Islamic Cooperation meeting in Türkiye. 

Barring a commando raid or even a nuclear strike, Iran’s underground Fordo uranium enrichment facility is considered out of reach to all but America’s “bunker-buster” bombs. Trump said he would put off his decision on military involvement for up to two weeks. 

The war erupted June 13, with Israeli airstrikes targeting Iran's nuclear and military sites, top generals and nuclear scientists. At least 722 people, including 285 civilians, have been killed in Iran and more than 2,500 wounded, according to a Washington-based Iranian human rights group. 

One Tehran resident, Nasrin, writhed in her hospital bed as she described how a blast threw her against a wall in her apartment. “I’ve had five surgeries. I think I have nothing right here that is intact,” she said Saturday.  

Another resident, Shahram Nourmohammadi, said he had been making deliveries when “something blew up right in front of me” at an intersection. 

Iran has retaliated by firing more than 450 missiles and 1,000 drones at Israel, according to Israeli army estimates. Israel’s multitiered air defenses have shot down most of them, but at least 24 people in Israel have been killed and hundreds wounded. 

Iran has long maintained its nuclear program is for peaceful purposes, but it is the only non-nuclear-weapon state to enrich uranium up to 60% — a short, technical step away from weapons-grade levels of 90%. Israel is widely believed to be the only Middle Eastern country with a nuclear weapons program but has never acknowledged it. 

Israeli Prime Minister Benjamin Netanyahu has said Israel’s military operation will continue “for as long as it takes” to eliminate what he called the existential threat of Iran’s nuclear program and ballistic missile arsenal. 

No date set for new talks 

Talks in Geneva on Friday failed to produce a breakthrough. European officials expressed hope for future discussions. Iran's foreign minister said he was open to further dialogue while emphasizing that Tehran had no interest in negotiating with the US while Israel continues to attack. 

“Iran is ready to consider diplomacy once again, and once aggression is stopped and the aggressor is held accountable for the crimes committed,” he told reporters. 

No date was set for a new round of talks. 

For many Iranians, updates remained difficult. Internet-access advocacy group NetBlocks.org said Saturday that limited internet access had again “collapsed.” A nationwide internet shutdown has been in place for several days. 

More attacks on Iranian military commanders 

Israel's opening attack killed three of Iran’s top military leaders: one who oversaw the armed forces, Gen. Mohammad Bagheri; one who led the paramilitary Revolutionary Guard, Gen. Hossein Salami; and the head of the Guard’s ballistic missile program, Gen. Amir Ali Hajizadeh. 

Israel's defense minister said Saturday the military has killed a Revolutionary Guard commander who financed and armed Hamas in preparation for the Oct. 7, 2023, attack on Israel that sparked the ongoing 20-month war in Gaza. 

Iranian officials did not immediately confirm Saeed Izadi's death, but the Qom governor's office said there had been an attack on a four-story apartment building and local media reported two people had been killed. 

Israel also said it killed the commander of the Quds Force's weapons transfer unit, who it said was responsible for providing weapons to Hezbollah and Hamas. Behnam Shahriyari was killed while traveling in western Iran, the military said. 



NBC: US Strikes Destroyed Only One of Three Iranian Nuclear Sites

This satellite image provided by Maxar Technologies shows the Isfahan enrichment facility in Iran after being hit by Israeli airstrikes, on Saturday, June 14, 2025. (Maxar Technologies via AP)
This satellite image provided by Maxar Technologies shows the Isfahan enrichment facility in Iran after being hit by Israeli airstrikes, on Saturday, June 14, 2025. (Maxar Technologies via AP)
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NBC: US Strikes Destroyed Only One of Three Iranian Nuclear Sites

This satellite image provided by Maxar Technologies shows the Isfahan enrichment facility in Iran after being hit by Israeli airstrikes, on Saturday, June 14, 2025. (Maxar Technologies via AP)
This satellite image provided by Maxar Technologies shows the Isfahan enrichment facility in Iran after being hit by Israeli airstrikes, on Saturday, June 14, 2025. (Maxar Technologies via AP)

A new US assessment has found that American strikes in June destroyed only one of three Iranian nuclear sites, NBC News reported on Thursday, citing current and former US officials familiar with the matter, Reuters said.

President Donald Trump rejected a military plan for further comprehensive strikes on Iran's nuclear program, which would have lasted several weeks, the report added.

Reuters could not immediately verify the report.