Israel's emergency medical service said 14 people including an 11-year-old girl were wounded during a missile attack that the military blamed on Iran and police said caused damage at several sites.
The military said it had "identified missiles launched from Iran towards the territory of the State of Israel" for the first time in about 20 hours, with air raid sirens activated across central Israel.
Another warning of incoming missile fire came less than an hour later, prompting alerts across large parts of northern and central Israel, according to the military's Home Front Command.
"EMTs and paramedics are providing medical treatment and evacuating to hospitals 14 casualties," the Magen David Adom emergency medical service said in a statement, including an 11-year-old girl in a serious condition with shrapnel injuries.
It said a 13-year-old boy and 36-year-old woman, also with shrapnel injuries, were in moderate condition and a further 11 casualties in "mild condition".
Sheba hospital in the Tel Aviv area said it was treating eight wounded people, including a child in "very critical condition", and six other children.
Authorities did not specify at how many sites people were injured. However, police reported damage at several sites in central Israel, sharing an image of what appears to be missile debris on a road.
AFP images from the city of Bnei Brak, outside of Tel Aviv, showed first responders and residents carrying small children out of an apartment building that was hit.
AFP footage and images from downtown Tel Aviv showed first responders at another impact site and a small crater on the road near the French embassy.
Iran has claimed it targets military objectives.
Due to military censorship rules in place in Israel since the start of the current war, sensitive military sites are closed to the public and the press, while other impact sites in populated areas are generally closed off until they are cleared of missile debris and unexploded ordnance.
Israeli media said cluster munitions, which explode mid-air and scatter bomblets across a wide area, were used in the latest attack.
Iran and Israel have previously accused each other of using cluster bombs.
