3 days, 640,000 Children, 1.3M Doses...the Plan to Vaccinate Gaza's Young against Polio

FILE - Palestinians displaced by the Israeli air and ground offensive on the Gaza Strip, walk through a dark streak of sewage flowing into the streets of the southern town of Khan Younis, Gaza Strip, on July 4, 2024. Health authorities and aid agencies are racing to avert an outbreak of polio in the Gaza Strip after the virus was detected in the territory's wastewater and three cases with a suspected polio symptom have been reported. (AP Photo/Jehad Alshrafi, File)
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3 days, 640,000 Children, 1.3M Doses...the Plan to Vaccinate Gaza's Young against Polio

FILE - Palestinians displaced by the Israeli air and ground offensive on the Gaza Strip, walk through a dark streak of sewage flowing into the streets of the southern town of Khan Younis, Gaza Strip, on July 4, 2024. Health authorities and aid agencies are racing to avert an outbreak of polio in the Gaza Strip after the virus was detected in the territory's wastewater and three cases with a suspected polio symptom have been reported. (AP Photo/Jehad Alshrafi, File)

The UN health agency and partners are launching a campaign starting Sunday to vaccinate 640,000 Palestinian children in Gaza against polio, an ambitious effort amid a devastating war that has destroyed the territory's healthcare system.

The campaign comes after the first polio case was reported in Gaza in 25 years — a 10-month-old boy, now paralyzed in the leg. The World Health Organization says the presence of a paralysis case indicates there could be hundreds more who have been infected but aren’t showing symptoms.

Most people who have polio do not experience symptoms, and those who do usually recover in a week or so. But there is no cure, and when polio causes paralysis it is usually permanent. If the paralysis affects breathing muscles, the disease can be fatal.

The vaccination effort will not be easy: Gaza’s roads are largely destroyed, its hospitals badly damaged and its population spread into isolated pockets.

WHO said Thursday that it has reached an agreement with Israel for limited pauses in the fighting to allow for the vaccination campaign to take place. Even so, such a large-scale campaign will pose major difficulties in a territory blanketed in rubble, where 90% of Palestinians are displaced.

How long will it take? The three-day vaccination campaign in central Gaza will begin Sunday, during a “humanitarian pause” lasting from 6 a.m. until 3 p.m., and another day can be added if needed, said Dr. Rik Peeperkorn, WHO’s representative in the Palestinian territories.

In coordination with Israeli authorities, the effort will then move to southern Gaza and northern Gaza during similar pauses, he said during a news conference by video from Deir al-Balah in central Gaza, according to The AP.

Who will receive the vaccine? The vaccination campaign targets 640,000 children under 10, according to WHO. Each child will receive two drops of oral polio vaccine in two rounds, the second to be administered four weeks after the first.

Where are the vaccination sites? The vaccination sites span Gaza, both inside and outside Israeli evacuation zones, from Rafah in the south to the northern reaches of the territory.

The Ramallah-based Health Ministry said Friday that there would be over 400 “fixed” vaccination sites — the most in Khan Younis, where the population density is the highest and there are 239,300 children under 10. Fixed sites include healthcare centers, hospitals, clinics and field hospitals.

Elsewhere in the territory, there will also be around 230 “outreach” sites — community gathering points that are not traditional medical centers — where vaccines will be distributed.

Where are the vaccines now? Around 1.3 million doses of the vaccine traveled through the Kerem Shalom checkpoint and are currently being held in “cold-chain storage” in a warehouse in Deir al-Balah. That means the warehouse is able to maintain the correct temperature so the vaccines do not lose their potency.

Another shipment of 400,000 doses is set to be delivered to Gaza soon.

The vaccines will be trucked to distribution sites by a team of over 2,000 medical volunteers, said Ammar Ammar, a spokesperson for UNICEF.

What challenges lie ahead? Mounting any sort of campaign that requires traversing the Gaza strip and interacting with its medical system is bound to pose difficulties.

The UN estimates that approximately 65% of the total road network in Gaza has been damaged. Nineteen of the strip's 36 hospitals are out of service.

The north of the territory is cut off from the south, and travel between the two areas has been challenging throughout the war because of Israeli military operations. Aid groups have had to suspend trips due to security concerns, after convoys were targeted by the Israeli military.

Peeperkorn said Friday that WHO cannot do house-to-house vaccinations in Gaza, as they have in other polio campaigns. When asked about the viability of the effort, Peeperkorn said WHO thinks “it is feasible if all the pieces of the puzzle are in place. ”

How many doses do children need and what happens if they miss a dose? The World Health Organization says children typically need about three to four doses of oral polio vaccine — two drops per dose — to be protected against polio. If they don’t receive all of the doses, they are vulnerable to infection.

Doctors have previously found that children who are malnourished or who have other illnesses might need more than 10 doses of the oral polio vaccine to be fully protected.

Are there side effects? Yes, but they are very rare.

Billions of doses of the oral vaccine have been given to children worldwide and it is safe and effective. But in about 1 in 2.7 million doses, the live virus in the vaccine can paralyze the child who receives the drops.

How did this outbreak in Gaza start? The polio virus that triggered this latest outbreak is a mutated virus from an oral polio vaccine. The oral polio vaccine contains weakened live virus and in very rare cases, that virus is shed by those who are vaccinated and can evolve into a new form capable of starting new epidemics.



What Is Known About Polio’s Return to the Gaza Strip 

Displaced kids sort through trash at a street in Deir al-Balah, central Gaza Strip, Tuesday, Aug. 27, 2024. (AP)
Displaced kids sort through trash at a street in Deir al-Balah, central Gaza Strip, Tuesday, Aug. 27, 2024. (AP)
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What Is Known About Polio’s Return to the Gaza Strip 

Displaced kids sort through trash at a street in Deir al-Balah, central Gaza Strip, Tuesday, Aug. 27, 2024. (AP)
Displaced kids sort through trash at a street in Deir al-Balah, central Gaza Strip, Tuesday, Aug. 27, 2024. (AP)

Health authorities in the Gaza Strip confirmed the first case of polio in 25 years earlier this month.

The infection and subsequent partial paralysis of the nearly year-old Abdul-Rahman Abu Al-Jidyan has hastened plans for a mass vaccination campaign of children across the Palestinian enclave starting on Sept. 1.

Three-day pauses in fighting in each of Gaza's three zones have been agreed by Israel and Hamas to allow thousands of UN workers to administer vaccines.

ORIGINS

The same strain that later infected the Palestinian baby, from the type 2 vaccine-derived polio virus that has also been detected in wastewater in some developed countries in recent years, was detected in July in six sewage samples taken in Khan Younis and Deir al-Balah.

It is not clear how the strain arrived in Gaza but genetic sequencing showed that it resembles a variant found in Egypt that could have been introduced from September 2023, the WHO said.

The UN health body says that a drop in routine vaccinations in the Occupied Palestinian Territories, including Gaza, has contributed to its re-emergence.

Polio vaccination coverage, primarily conducted through routine immunization, was estimated at 99% in 2022 and fell to 89% in 2023. Health workers say the closure of many hospitals in Gaza, often because of Israeli strikes or restrictions on fuel, has contributed to lower vaccination rates. Israel blames Hamas, saying they use hospitals for military purposes.

Aid workers say poor sanitation conditions in Gaza where open sewers and trash piles are commonplace after nearly 11 months of war have created favorable conditions for its spread.

MASS VACCINATIONS

Israel's military and the Palestinian armed group Hamas have agreed to three separate, zoned three-day pauses in fighting to allow for the first round of vaccinations.

The campaign is due to start in central Gaza on Sunday with three consecutive daily pauses in fighting, then move to southern Gaza, where there would be another three-day pause, followed by northern Gaza. There is an agreement to extend the pause in each zone to a fourth day if needed.

The vaccines, which were released from global emergency stockpiles, have already arrived in Gaza and are due to be issued to 640,000 children under 10 years of age.

They will be given orally by some 2,700 health care workers at medical centers and by mobile teams moving among Gaza's hundreds of thousands of people displaced by the war, UN aid workers say.

The World Health Organization says that a successful roll-out requires at least 95% coverage.

The Israeli military's humanitarian unit (COGAT) said that the vaccination campaign would be conducted in coordination with the Israeli military "as part of the routine humanitarian pauses that will allow the population to reach the medical centers where the vaccinations will be administered".

A second round is planned in late September.

RISKS

The Gaza case which is vaccine-derived is seen as a setback for the global polio fight which has driven down cases by more than 99% since 1988 thanks to mass vaccination campaigns.

Wild polio is now only endemic in Pakistan and Afghanistan although more than 30 countries are still listed by the WHO as subject to outbreaks, including Gaza's neighbors Egypt and Israel.

The World Health Organization has warned of the further spread of polio within Gaza and across borders given the poor health and hygiene conditions there.

Poliomyelitis, which is spread mainly through the faecal-oral route, is a highly infectious virus that can invade the nervous system and cause paralysis and death in young children with those under 2 years old most at risk. In nearly all cases it has no symptoms, making it hard to detect.